Endocrine Abstracts

IntroductionOnce thought to typify type 1 diabetes mellitus (T1DM), diabetic ketoacidosis (DKA) in people with type 2 diabetes mellitus (T2DM) is also now increasingly recognized. We explored the clinical and biochemical differences in DKA in the two types of diabetes.MethodsThis retrospective cohort study included all the DKA episodes from April 2014 to September 2020 at a large tertiary care centre in West ...

IntroductionCoronavirus disease (COVID-19) in people with diabetes is associated with a disproportionately worse prognosis. DKA is an acute complication of diabetes with a mortality rate of approximately 0.67%. Little is known about natural history of DKA in the presence of COVID-19 infection. This study aimed to explore the effects of COVID-19 infection on presentation, clinical course and outcome in patients presenting with DKA.M...

Background: Diabetic ketoacidosis (DKA) is an acute endocrine emergency in people with diabetes. Paucity of information prevails over sex- and age-related variations in patients presenting with DKA.Objective: To assess the impact of age and sex in the clinical course, presentation, outcome and management of DKA in people with type 1 (T1DM) and type 2 diabetes (T2DM).Methods: We included all DKA from April 2014 to September 2020 in ...

Objectives: Limited evidence exists studying the impact of ethnicity on diabetic ketoacidosis (DKA). We aimed to study the impact of ethnicity on presentation, management and outcome of DKA in type 1 (T1DM) and type 2 (T2DM) diabetes.Methods: All DKA episodes from April 2014 to September 2020 in a UK tertiary care centre were identified. Data were collected on diabetes type, demographics, biochemical and clinical features on admission, and DKA management...

Objectives: We explored the differences in severity and outcomes of diabetic ketoacidosis (DKA) in people with type 1 (T1DM) and type 2 diabetes (T2DM).Methods: All DKA episodes from April 2014 to September 2020 at a tertiary care centre in the United Kingdom were identified. People admitted with DKA were classified as having T1DM or T2DM based on previously established diagnosis, autoantibody status, and/or phenotypic features. We compared the differenc...