Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep39 | Adrenal and Cardiovascular Endocrinology | ECE2020

Effects of endogenous hypercortisolism on selected Angio-miRs expression in humans

Kawa Miłosz , Sobuś Anna , Łuczkowska Karolina , Litwińska Zofia , Bajerski Norbert , Osowicz-Korolonek Lilianna , Cymbaluk-Płoska Aneta , Wnęk Szymon , Dąbkowska Elżbieta , Walczak Mieczysław , Syrenicz Anhelli , Machaliński Bogusław

Background and Aims: Higher cortisol levels are associated with cardiovascular mortality in the elderly resulting from potential angiostatic effects of glucocorticoids (GCs). These features are replicated in patients with endogenous GCs excess (Cushing’s syndrome) as well as with exogenous hypercortisolism due to excessive pharmacological GCs usage. Both groups present the augmented cardiovascular disease event rate. GCs may also adversely influence remodeling after myoc...