Searchable abstracts of presentations at key conferences in endocrinology

ea0055wa10 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Rapidly progressive polyuria, polydipsia and headache – an unusual case of central diabetes insipidus

Thurtell Craig , Mackie Alasdair

A previously well 49 year old woman was referred to our endocrine service with a compelling 4 month history of polyuria and polydipsia. Her 24 h fluid intake was estimated to be 12 l with 4 l of this taken overnight; these estimates had doubled in the 2 months since referral. Due to the development of an increasingly severe frontal headache, her GP organised a CT head scan which was largely unremarkable aside from a ‘slight fullness’ to the pituitary gland. Pituitary...

ea0055we11 | Workshop E: Disorders of the adrenal gland | SFEEU2018

You can lead a patient to hospital, but you can’t make him have an adrenalectomy

Thurtell Craig , Mackie Alasdair

A 42 year old man was referred to the acute medical unit with accelerated hypertension in March 2015. He presented with headache and blurred vision due to hypertensive retinopathy. Pre-treatment BP was 186/131 mmHg. Initial treatment included amlodipine, bendroflumethiazide and losartan. Prior to discharge, a 24 hour urine collection showed a significantly elevated urinary noradrenaline level (3091 nmol/d, reference 0–473). Referral was made to the cardiovascular risk cli...

ea0034p359 | Steroids | SFEBES2014

Does recurrent hypoglycaemia, a known activator of the HPA axis, alter the diurnal pattern of cortisol release?

George Priya , Mackie Alasdair , Connell John , McCrimmon Rory

In population studies, premature cardiovascular disease is associated with cortisol dysregulation. Recently, recurrent hypoglycaemia in individuals with type 1 diabetes (T1D) was reported to be associated with increase carotid intima–media thickness. Hypoglycaemia is a potent activator of the hypothalamo-pituitary–adrenal axis (HPA axis) with eventual release of cortisol. We hypothesized that individuals with T1D who experience recurrent hypoglycaemia might demonstra...