Endocrine Abstracts

Objective: decreased survival and higher cardiovascular risk have been reported in a UK cohort of RTHβ patients, but there is no evidence from other countries.Methods: retrospective study of an Italian cohort of RTHβ patients, carrying heterozygous pathogenic variants in the THRB gene and diagnosed in the period between 1984 and 2023. We collected records at diagnosis of 284 cases, whereas longitudinal data were available in 249 RTH&#9...

The incidence of Neuroendocrine Neoplasm (NEN) and related carcinoid syndrome (CS) increased markedly in recent decades, and women appear to be more at risk than men. As per other tumors, gender may be relevant in influencing the clinical and prognostic characteristics. Unfortunately, there are no studies designed to answer this question in the literature. The present multicentric study was designed to evaluated gender differences, if any, in clinical presentation and outcomes...