Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1504 | Pituitary Clinical | ICEECE2012

Hyperprolactinemia: prolactinoma or pregnancy?

Belo S , Magalhaes A , Carvalho D

Introduction: High prolactin levels may have several etiologies including the presence of a prolactin producing pituitary adenoma or the treatment with drugs of different classes. Certain physiological states, from which pregnancy stands out, are also characterized by elevated levels of prolactin.Case: Woman, 28 years old, with no relevant medical history or chronic medication apart from oral contraceptives, begins with amenorrhea in May 2010, without ga...

ea0026p654 | Clinical case reports | ECE2011

Type II polyglandular syndrome: a case report

Belo S , Magalhaes A , Carvalho D

Introduction: The combination of two or more, autoimmune, endocrine dysfunctions defines the presence of polyglandular syndromes.Case report: Female patient, 43 years old, history of type 1 diabetes for 23 years and autoimmune hypothyroidism for 7 years, with no other relevant clinical history and without family history of autoimmune endocrinopathies. She was under therapy with insulin and levothyroxine. She came into the Endocrinology Department in May ...

ea0032p664 | Male reproduction | ECE2013

Male pseudohermaphroditism Leydig cell hypoplasia

Belo Sandra , Magalhaes Angela , Carvalho Davide

Introduction: LH receptor plays an important role in sexual development and reproductive function. Mutations of this receptor lead to the development of three clinical conditions: Leydig cell hypoplasia, hypergonadotropic hypogonadism with primary amenorrhea and familial male limited precocious puberty. The first two entities result from inactivating mutations. In Leydig cell hypoplasia, with autosomal recessive inheritance, the phenotypic spectrum correlates with the degree o...

ea0032p939 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Pituitary abscess: a possible cause of hypopituitarism

Belo Sandra , Magalhaes Angela , Carvalho Davide

Background: Generously supported by IPSEN)-->Pituitary abscess is a rare but potentially fatal entity. It represents ~0.2–1% of all pituitary lesions. The symptoms are usually nonspecific. The proper interpretation of imaging studies is of extreme importance to the differential diagnoses.Case: Man, 40 years old, begins complaining of occipital headache (25.04.2011), initially with good response to treatmen...

ea0029p115 | Adrenal medulla | ICEECE2012

Pheochromocytomas: a single centre experience

Belo S. , Magalhaes A. , Nogueira C. , Carvalho D.

Introduction: Catecholamine-secreting tumors (pheochromocytomas and paragangliomas) are rare intra and extra-adrenal neoplasms, probably occurring in less than 0.2% of patients with hypertension. Serious morbidity and mortality rates are associated with these tumors which are related to the effects of catecholamines on various organs, especially those of the cardiovascular system.Methods: We reviewed the cases of pheochromocytomas and paragangliomas that...

ea0032p139 | Calcium and Vitamin D metabolism | ECE2013

Familiar hypocalciuric hypercalcemia a rare cause of hypercalcemia

Belo Sandra , Magalhaes Angela , Capela Joao , Carvalho Davide

Introduction: Familial hypocalciuric hypercalcemia (FHH) is caused by inactivating autosomal dominant mutations with high penetrance of CaSP gene. Contrary to severe neonatal hyperparathyroidism, caused by homozygous inactivation of the gene, familial hypocalciuric hypercalcemia is usually associated with inactivating variants in heterozygoty.Case: Male patient, 73 years, with history of Behçet’s disease and pulmonary sarcoidosis, was refered f...

ea0032p632 | Growth hormome IGF axis – basic | ECE2013

Glucose metabolism abnormalities in a population of acromegalic patients

Nogueira Claudia , Belo Sandra , Vinha Eduardo , Magalhaes Angela , Carvalho Davide

Introduction: There is a well-established association between acromegaly and insulin resistance (IR). The abnormalities in glucose metabolism may be an important risk factor of cardiovascular morbid-mortality in these patients.Objective: Evaluation of glucose metabolism abnormalities in a population of naïve acromegalic patients and its relationship with delay in diagnosis, gender, levels of insulin like growth factor 1 (IGF1) and GH.<p class="a...

ea0026p612 | Clinical case reports | ECE2011

Iatrogenic hypoadrenalism: a case report

Mesquita J , Varela A , Magalhaes A , Correia F , Carvalho D

Introduction: Psoriasis is a chronic skin disease with a prevalence of 0.6 to 4.8%. Among the possible treatments, we highlight topic corticosteroids that can cause not only different local side effects (skin fragility and atrophy, striae, purpura, acne, telangiectasia, hypertrichosis) but also systemic side effects, including diabetes mellitus (DM), hypertension (HT), Cushing’s syndrome and hypothalamic–pituitary–adrenal (HHA) axis suppression.<p class="abs...

ea0090ep83 | Adrenal and Cardiovascular Endocrinology | ECE2023

Primary adrenal insufficiency in the context of small-cell neuroendocrine prostate cancer

de Brito Marques Francisca , Magalhaes Helena , Ferreira Joana Lima , de Carvalho Francisco Simoes , Marques Ana Paula

Introduction: The small-cell neuroendocrine prostate carcinoma (SCPC) is rare, highly aggressive and usually transforms from prostate adenocarcinoma (PAC) after androgen deprivation therapy (ADT).Case Report: A 66-year-old man had a three-year history of high-grade PAC with high burden disease (abdominal lymph node and bone metastasis) at presentation (09/2019). On the initial staging evaluation, the CT scan documented a 20 mm left adrenal nodule compati...

ea0049ep871 | Clinical case reports - Pituitary/Adrenal | ECE2017

Adipsic diabetes insipidus – a diagnostic and therapeutic challenge

Magalhaes Daniela , Esteves Cesar , Costa Maria Manuel , Rodrigues Pedro , Carvalho Davide

Introduction: In diabetes insipidus (DI) the serum sodium is often in the high normal range, required to provide the ongoing stimulation of thirst to replace the urinary losses. Marked hypernatremia can occur if a central lesion impairs both ADH release and thirst.Case report: A 57-year-old woman presented with dysuria, polyuria and fever. She was medicated with ciprofloxacin, however, she maintained symptoms, accompanied in the next day by nausea, vomit...