Searchable abstracts of presentations at key conferences in endocrinology

ea0022p39 | Adrenal | ECE2010

The measurement of epicardial fat thickness is an index of cardiometabolic risk in patients with adrenal incidentaloma

Iorio Laura , Zelaschi Roberta , Coman Calin , Malavazos Alexis Elias , Dogliotti Giada , Corsi Massimiliano Marco , Ambrosi Bruno

An augmented cardiovascular risk is present in adrenal incidentalomas (AI), as in overt hypercortisolism. Recent studies recommended epicardial fat (EF) thickness as a new marker of visceral adiposity and an indicator of cardiometabolic risk.In this study, we evaluated the possible relationship between EF thickness, indices of left ventricular (LV) hypertrophy and adipocytokines levels in AI.We studied 26 patients with AI (62.3&#17...

ea0014p102 | (1) | ECE2007

Cortisol excess, inflammatory markers and echocardiographic alterations in adrenal incidentalomas

Ermetici Federica , Malavazos Alexis , Coman Calin , Morricone Lelio , Corsi Massimiliano , Ambrosi Bruno

An increased cardiovascular risk has been described in patients (pts) with adrenal incidentaloma (AI), similarly to pts with overt CushingÂ’s syndrome (CS). Some echocardiographic abnormalities and alterations in adipokine secretion involved in insulin resistance, inflammation and atherosclerosis have been reported in pts with CS. In this study the possible correlation between echocardiographic parameters and adipokine levels in pts with AI was evaluated.<p class="abst...

ea0037gp.10.09 | Calcium, Vitamin D and Bone | ECE2015

Serum cystatin C levels were correlated with cardiometabolic features and cardiovascular diseases in patients with primary hyperparathyroidism

Verdelli Chiara , Ermetici Federica , Filopanti Marcello , Verga Uberta , Passeri Elena , Dito Giorgia , Malavazos Alexis Elias , Mapelli C , Raggi M E , Corbetta Sabrina

Patients with primary hyperparathyroidism (PHPT) are at risk of chronic kidney disease (CKD). PHPT patients (n=190, 146 females and 44 males, aged 59.7±14.2 years) and non-hypertensive, non-diabetic age- and sex-matched healthy controls were evaluated for serum cystatin C and creatinine. PHPT patients and controls with established CKD were excluded. Serum cystatin C was measured by immunonephelometric assay and calculation of estimated glomerular filtration rate ...

ea0035p766 | Obesity | ECE2014

Vertebral bone marrow fat is increased in obese women: relationship with epicardial fat

Ermetici Federica , Briganti Silvia , Delnevo Alessandra , Cannao Paola , Secchi Francesco , Leo Gianni Di , Bandera Francesco , Dozio Elena , Romanelli Massimiliano Marco Corsi , Sardanelli Francesco , Morricone Lelio , Malavazos Alexis Elias

Introduction: Bone marrow fat is considered a risk factor for osteoporosis and fragility fracture. It is not clear if bone marrow adiposity is increased in obesity and how it relates to other compartments of adipose tissue, in particular visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and epicardial adipose tissue (EAT).Aim: To evaluate bone marrow adiposity in obese as compared with normal weight women.Design: Tw...

ea0022p632 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Modification of epicardial fat thickness in adult GHD patients after short-term replacement therapy with rhGH

Ferrante Emanuele , Giavoli Claudia , Malavazos Alexis , Ermetici Federica , Bergamaschi Silvia , Ronchi Cristina , Coman Calin , Passeri Elena , Corbetta Sabrina , Lania Andrea , Ambrosi Bruno , Spada Anna , Beck-Peccoz Paolo

Adult GH deficiency syndrome is characterized by visceral obesity, dyslipidemia, insulin resistance and is associated with an increased cardiovascular risk. Epicardial adipose tissue, giving its relationship with abdominal visceral adiposity, coronary artery disease, cardiac morphology and function and metabolic syndrome, has been proposed as cardio-metabolic risk indicator. In this study, we evaluated the echocardiographic epicardial fat thickness in 14 patients (8 M and 6 F,...