Searchable abstracts of presentations at key conferences in endocrinology

ea0016p96 | Bone and calcium | ECE2008

Effects on bone turnover and bone mineral density of levothyroxine suppressive therapy in patients with benign nodular goiter

Duarte Leone , Silva-Nunes Jose , Lopes Ana-Filipa , Malheiro Fernando

Introduction: Thyroid hormones play an important role in bone metabolism. The potential action of prolonged levothyroxine therapy on bone mass reduction is still a matter of debate.Objective: The aim of the present study was to assess the effects of levothyroxine treatment on bone mineral density (BMD) and biochemical bone turnover markers.Methods: We determined thyroid function – TSH and free T4 (FT4), r...

ea0020p392 | Diabetes and Cardiovascular | ECE2009

Anthropometric determinants of adiponectin levels in obese and non obese premenopausal women

Silva-Nunes Jose , Duarte Leone , Veiga Luisa , Melao Alice , Brito Miguel , Malheiro Fernando

Background: Adiponectin is an important adipokine to which have been attributed anti-diabetic and anti-atherogenic properties. Excess of abdominal fat deposition is undoubtedly assumed as a cardiometabolic risk factor. It has been hypothesized that peripheral deposition of fat could exert a protective effect in cardiometabolic profile.Aims: To evaluate the influence of anthropometric parameters on adiponectin levels in both obese and normal-weight premen...

ea0020p324 | Clinical case reports and clinical reports | ECE2009

Insulin autoimmune syndrome in a patient with type 2 diabetes: a case report

Duarte Leone , Silva-Nunes Jose , Peerally Zulmira , Gomes Lurdes , Rogado Maria-Cristina , Lopes Ana-Filipa , Raposo Joao-Filipe , Malheiro Fernando

Introduction: Insulin autoimmune syndrome (IAS) is a clinical condition characterized by the presence of autoantibodies to insulin or insulin receptors in patients not previously treated with insulin. This syndrome has been reported mainly in Asia, and it is a rare cause of hypoglycemia in Caucasians. So far there are no reports of IAS in patients with type 2 diabetes mellitus never treated with insulin.Case report: The authors describe a 59-year-old Cau...

ea0020p352 | Diabetes and Cardiovascular | ECE2009

Coronary heart disease risk reduction in obese patients submitted to adjustable gastric band

Duarte Leone , Silva-Nunes Jose , Lopes Ana-Filipa , Santos Cristina , Coutinho Jose-Mario , Botelho Maria-Manuel , Albuquerque Antonio , Malheiro Fernando

Background: Obesity is related to an increased cardiovascular risk, namely coronary heart disease risk (CHDr). Type 2 diabetes (T2D) is frequently associated with obesity and, by itself, is an important CHDr factor. Interventions that induce weight loss would be expected to attenuate CHDr in obese patients.Aims: To evaluate variation in cardiovascular risk profile one year after adjustable gastric banding (AGB), in obese patients (with and without T2D); ...