Searchable abstracts of presentations at key conferences in endocrinology

ea0011p857 | Thyroid | ECE2006

A novel test with recombinant human TSH for the differential diagnosis of congenital hypothryoidism in pediatric age

Fugazzola L , Weber G , Mannavola D , Vannucchi G , Carletto M , Longari V , Persani L , Beck-Peccoz P

Congenital hypothyroidism (CH) affects 1:2.000–3.000 newborns. In most cases, the cause is a developmental defect (dysgenesia) or an arrested migration (ectopia) of the thyroid gland. In the remaining cases TSH resistance or defects in iodide transport or thyroid hormonogenesis account for CH. The differential diagnosis is aimed to recognize permanent CH forms and to achieve an etiologic diagnosis for accurate management and genetic counselling. Appropriate investigations...