Endocrine Abstracts

Thyroid C-cells, as a second type of endocrine cell population within thyroid, produce and secrete peptide hormone calcitonin (CT). This hypocalcemic hormone acts as an inhibitor of bone resorption. The aging is a complex process that alters various cellular functions. Therefore, the aim of this study was to examine the aging-related changes in the structure and function of CT-producing thyroid C-cells in male Wistar rats, using histomorphometric, ultrastructural and biochemic...

Background: Hypopituitarism can be expressed throughout many symptoms and can stay unrecognized for a long time. Xanthogranulomas are extremely rare in sellar region, with prevalence of ~0.6% in reported pituitary tumours and are presented with visual disturbance, hyperprolactinemia, diabetes insipidus and/or hypopituitarism. Its ethiopathogenesis is still not certain, but it can be of primary or systemic cause. It’s almost always diagnosed postoperatively and has good ou...

Calcitonin (CT) is a hypocalcemic hormone produced by thyroid C-cells that acts as an bone antiresorptive agent. The other endocrine cell population in thyroid, called follicular cells produce thyroid hormones (TH) which also affect bone turnover. In this study, we evaluated the effects of salmon CT administration on structure and function of both CT and TH producing thyroid cells as well as trabecular bone microarchitecture in orchidectomized (Orx) middle-aged rats. Fifteen-m...