Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep435 | Calcium and Bone | ECE2024

A tertiary center experience on denosumab treatment

Balasa Alexandra , Manole Andreea , Dobre Ramona , Sorohan Madalina , Poiana Catalina

Background: Osteoporosis is a chronic metabolic bone disease, highly prevalent in the elderly population, especially in postmenopausal women. Denosumab is a potent anti-resorptive drug, which can be used as an initial therapy or as an alternative therapy in the treatment of osteoporosis.Objective: We aimed to analyze the characteristics of patients, the evolution of bone mass density (BMD) and trabecular bone score (TBS) and the factors associated with f...

ea0099p37 | Calcium and Bone | ECE2024

Intrathyroidal parathyroid adenoma: Two case reports

Andrei Anca Maria , Manole Andreea , Ungureanu Alicia , Varlan Delia , Dobre Ramona , Burcea Iulia , Poiana Catalina

Introduction: The basis of treatment of primary hyperparathyroidism (pHPT) is parathyroidectomy of the responsible lesion, and thus, preoperative localization is important. Ectopic parathyroid adenomas are rare, and they can be accounted for persistent or recurrent hyperparathyroidism. An intrathyroidal parathyroid adenoma (IPA) is an ectopic variant where the adenoma is either partly (>50%) or completely enveloped by the thyroid gland. The incidence of IPAs ranges from 0....

ea0099ep1015 | Endocrine-Related Cancer | ECE2024

Rare primary sites of neuroendocrine tumors:two case reports

Manole Andreea , Andrei Anca , Ungureanu Alicia , Anne-Marie Stefan Andreea , Dobre Ramona , Burcea Iulia-Florentina , Poiana Catalina

Introduction: Neuroendocrine neoplasms are rare heterogeneous malignancies originating from neuroendocrine cells throughout the body. The most common primary sites are the gastrointestinal and respiratory tracts, but can originate from almost any organ, some in unusual locations. The diagnosis is based on the confirmation of the endocrine nature of the tumor and secondly the confirmation of its primary nature. We describe two cases with a very rare primary localization of neur...

ea0099ep1162 | Thyroid | ECE2024

Intrathyroidal CMT with high level of calcitonin

Ungureanu Miruna-Alicia , Dobre Ramona , Manole Andreea , Andrei Anca , Burcea Iulia-Florentina , Octavian Alexandrescu Dan , Poiana Catalina

Introduction: Medullary thyroid carcinoma (MTC) is defined as a rare neuroendocrine tumor originated from the parafollicular C cells of the thyroid, noted for the ability of secreting calcitonin and other peptides. MTC poses a high risk of mortality if left untreated as the tumoral cells can invade nearby tissues, lymph nodes, lymphatic or blood vessels and, ultimately, other organs. Calcitonin is key in the evaluation and treatment protocol as its basal serum levels tend to b...

ea0102137 | Diabetes, Obesity and Metabolism | EYES2024

Partial familial lipodistrophy - 2 case reports

Gidei Alexandra-Irina , Mohora Alexandra , Andrei Anca , Manole Andreea , Ungureanu Alicia , Dobre Ramona , Burcea Iulia-Florentina , Poiana Catalina

Introduction: Familial partial lipodistrophy (FPL) is a rare genetic disorder characterized by a progressive loss of adipose tissue from various areas of the body. Associated complications include diabetes mellitus, hypertriglyceridemia, non-alcoholic fatty liver disease, polycystic ovaries, acanthosis nigricans, premature atherosclerosis.Case presentation: The first case is about a 19-years-old woman, known with insulinoresistance (under metformin) and ...