Endocrine Abstracts

Background: Intranasal steroids are commonly used for allergic rhinitis, rhinosinusitis and nasal polyps as they are considered safe in terms of long-term adverse effects profile due to favourable pharmacokinetic characteristics as compared to other oral and inhaled steroids. Some are also available over the counter without prescription.Case: We report a patient with iatrogenic Cushing”s syndrome and secondary adrenal insufficiency due to chronic in...

Hyponatremia due to water intoxication is often associated with mental disorders like schizophrenia and psychosis. Patients usually present with headaches, seizures and altered consciousness. The mainstay treatment in these cases is fluid restriction. A 31-year-old man was brought to the hospital following a fall and disorientation. He had a history of Schizophrenia which had been well controlled on risperidone. A few weeks before this presentation, he drank about 20 litres of...

Case History: A 68-year-old gentleman was admitted to the hospital following a history of weight loss, lethargy, tiredness for about 6 months. His past history includes hiatus hernia, esophagitis and kidney stones. He reported taking over the counter vitamin D (60,000 IU daily) for more than 2 years. He was not on any other regular medications.Investigations: His initial investigations showed acute kidney injury with severe PTH independent hypercalcaemia...

Introduction: Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours with no standardised protocol for treatment. 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is an emerging treatment option for patients with metastatic and/or inoperable PPGL, and with low toxicity. We present our experience with PRRT in advanced PPGL, treated in a ENETS Centre of Excellence.Materials and Methods: 165 patients with...

Introduction: Gestational trophoblastic disease (GTD) is a group of disorders arising from abnormal proliferation of placental trophoblasts. Hydatiform mole (molar pregnancy) is a premalignant condition which is further devided in to partial and complete mole. Incidence of molar pregnancy is estimated to be 1 in 1000 pregnancies. Hyperthyroidism is one of the rare complications of molar pregnancy which, if not detected and treated, can lead to adverse consequences. We describe...

Introduction: Metastatic phaeochromocytomas (PCC) and paragangliomas (PGL), collectively known as metastatic PPGL (mPPGL), represent uncommon neuroendocrine tumours for which no standardized treatment guidelines exist. The emerging therapeutic modality employing 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) has exhibited favourable tolerability in the management of these patients.Methods: In this...