Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep11 | Adrenal cortex (to include Cushing's) | ECE2016

ARMC5 mutation and Cushing syndrome due to bilateral macronodular adrenal hyperplasia – case report

Manuel Costa Maria , Oliveira Joana , Luis Castedo Jose , Magalhaes Joao , Carvalho Davide

Introduction: Bilateral macronodular adrenal hyperplasia ACTH-independent (BMAH) represents less than 1% of the causes of CushingÂ’s syndrome (CS). Studies have shown that mutations in the gene ARMC5 are a common cause of family BMAH and are associated with severe clinical disease and the development of meningiomas.Case report: 64-years-old man presented to our consult due to bilateral macronodular adrenal hyperplasia. He had diabetes mellitus, arter...

ea0041ep52 | Adrenal cortex (to include Cushing's) | ECE2016

Adrenal leiomyoma: a rare cause of adrenal incidentaloma

Manuel Costa Maria , Belo Sandra , Souteiro Pedro , Magalhaes Joao , Carvalho Davide

Introduction: Leiomyomas are benign tumors originating from the smooth muscle cells. They occur more frequently in the uterus and in the gastrointestinal system. Adrenal leiomyomas are rare tumors arising from the smooth muscle of the adrenal vein and its tributaries.Case report: Man, 72-years-old, referred to Endocrinology in the context of an adrenal incidentaloma (20 mm maximum diametre) detected in abdominal-pelvic CT performed for the study of splen...

ea0041ep312 | Clinical case reports - Pituitary/Adrenal | ECE2016

Insipid diabetes and acute myeloid leukemia: genotypic/phenotypic correlation?

Manuel Costa Maria , Belo Sandra , Souteiro Pedro , Luis Castedo Jose , Carvalho Davide

Introduction: Central diabetes insipidus (CDI) is a rare complication of acute myeloid leukemia (AML) occurring in less than 0.6% of patients. It is associated with genetic changes in chromosomes 3 and 7. CDI may precede; occur simultaneously or after the diagnosis of AML.Case report: 51-year-old man, with no relevant past medical history, began complaining with polyuria, polydipsia, weakness and weight loss in March 2015.The patient was evaluated in the...

ea0081p741 | Thyroid | ECE2022

Efficacy of radioactive iodine treatment in Graves Disease using a calculated 131I dose and predictive factors of success in a Portuguese cohort

Franco Sara , Teixeira Ferreira Rita , Cardoso Ferreira Ines , Quitalo Ana , Barbosa David , Manuel Costa Maria , Vara Luiz Henrique , Raimundo Luisa , Isabel Santos Ana

Aim: Dose corrected for thyroid gland size is one of the methods used to determine radioactive iodine (RAI) activity for patients with Graves disease (GD). This study was aimed to investigate the real-world success rate of this method and the predictors of success after first treatment.Methods: This is a retrospective study of 80 patients with GD treated between 2014 and 2020 in a tertiary referral hospital in Almada, Portugal. The successful group was d...

ea0041ep793 | Obesity | ECE2016

Obstructive sleep apnoea syndrome – longitudinal outcomes and improvement predictors after bariatric surgery

Bettencourt-Silva Rita , Magalhaes Daniela , Souteiro Pedro , Sergio Neves Joao , Castro Oliveira Sofia , Manuel Costa Maria , Saavedra Ana , Bettencourt-Silva Marilia , Almeida Leonor , Drummond Marta , Queiros Joana , Varela Ana , Freitas Paula , Correia Flora , Carvalho Davide , AMTCO group Davide

Background: Bariatric surgery has been associated with a decrease in multiple obesity-related comorbidities including obstructive sleep apnoea syndrome (OSA). This study aims to access the OSA evolution in obese patients who underwent bariatric surgery.Methods: Retrospective longitudinal study of a population of obese patients who underwent bariatric surgery between January/2010 and July/2014 in our centre. Only patients who have undergone polysomnograph...