Endocrine Abstracts

Background: Thyroid damage is known to occur during experimental iodine-induced goiter. MicroRNAs (miRNAs) are a class of small non-coding RNAs regulating gene expression. Dysregulation of specific miRNAs can interfere with tissue homeostasis. The purpose of this study was to investigate the dynamic expression profiles of miRNAs during adequate or mild-excess iodine supplementation in the iodine-deficient thyroid.Methods: Hyperplastic goiter was induced ...