Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep241 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Detection of subclinical diabetic autonomic neuropathy by reflex cardiovascular testing

Mahdy Maram , Gadalla Fadila , Khorshid Hazem

Background: Diabetic autonomic neuropathy (DAN) is among the least recognized and understood complication of diabetes despite its significant negative impact on survival and quality of life in people with diabetes. Diabetic neuropathies including cardiac autonomic neuropathy (CAN), are a common chronic complication of type 1 and Type 2 diabetes and confer a high morbidity and mortality to diabetic pateints. The reported prevalence of CAN varies greatly depending on the criteri...

ea0041ep838 | Obesity | ECE2016

Association of sex hormones with metabolic syndrome among Egyptian males

Mahdy Maram , Eloraby Hussein , Zaky Eman

Metabolic Syndrome (Met S), is associated with increased risk of cardiovascular disease (CVD) and mortality, the presence of 1 or 2 components of the (MetS) increases overall mortality compared with the absence of any component of the (MetS). Epidemiological studies have shown that low testosterone is associated with MetS. While testosterone levels decline with age, Estradiol (E2) levels remain relatively stable resulting in a decreased testosterone: E2 ratio (T:E), Whether th...

ea0041gp80 | Diabetes (1) | ECE2016

Study of serum fetuin-A in male patients with type 1 diabetes mellitus: association with insulin resistance and possible role of metformin therapy

Mahdy Maram , Shereba Nermin , Ahmed Iman , Abdelsalam Mona , Eid Yara , Mansour Hany

Type 1 diabetes mellitus (DM) is a multi system disease with both biochemical and anatomic/structural consequences. A number of components of the metabolic syndrome may be observed in patients with type 1 diabetes. It was suggested that treating obese adolescents with insulin resistance using metformin is an option for patients without response to traditional lifestyle change. It was reported that fetuin-A could inhibit insulin receptor tyrosine kinase activity and induced a l...

ea0037ep494 | Diabetes (complications & therapy) | ECE2015

Angiopoietin 1 in patients with type 2 diabetes mellitus and diabetic retinopathy

El Sattar El-Deeb Abd , Halawa Mohamed , Saad Ahmed , Sabry Inas , Mahdy Maram , Abd El Aziz Mohamed , Roshdy Nagwa

Background: Diabetic retinopathy (DR) is a clinically well-defined sight-threatening complication in type 2 diabetes. Angiopoietin 1 (Ang1) has been shown to promote endothelial cell survival without causing proliferation, stabilise endothelial interactions with surrounding support cells and can block the vascular permeability effects of vascular endothelial growth factor (VEGF). More recent data suggest that balance between these growth factors may affect vascular endothelial...