Searchable abstracts of presentations at key conferences in endocrinology

ea0078p59 | Pituitary and Growth | BSPED2021

Lymphocytic Hypophysitis: A rare entity in children - Case report

Agrawal Pankaj , Bhushan Arya Ved , Maratos Eleni , Bodi Istvan , Al Busaidi Ayisha , Wei Christina , Kapoor Ritika R , Aylwin Simon , Buchanan Charles R

Introduction: Pituitary inflammation (Hypophysitis) is rare in paediatric population and usually results in pituitary enlargement and hypopituitarism. Hypophysitis can be either primary (most commonly lymphocytic, granulomatous or xanthomatous disease) or secondary (consequent to systemic diseases, immunotherapy or alternative sella-based pathologies). We describe the clinical presentation and management of apparent primary lymphocytic hypophysitis in an adolescent girl. Case ...

ea0081p175 | Pituitary and Neuroendocrinology | ECE2022

Low post-operative cortisol after TSS for pituitary surgery predicts short term but not long term remission

Karunakaran Vanitha , Okasha Mohamed , W Thomas Nick , Barazi Sinan , Maratos Eleni , C Whitelaw Benjamin , Gilbert Jackie , V Carroll Paul , Shapey Jonathan , J B Aylwin Simon

Background: It is generally accepted that a post-operative cortisol of <50 nmol/l is a good predictor of long-term remission following trans-sphenoidal surgery (TSS).Aim: We wished to determine the rate of late recurrence and need for consequent intervention in patients who had initial biochemical remission after TSS for pituitary dependent Cushing’s.Methods: We performed a retrospective analysis of our patients who underw...

ea0070aep560 | Pituitary and Neuroendocrinology | ECE2020

Proliferation index (Ki67) is a powerful predictor of recurrence in pituitary adenoma

Logan Ellis Hugh , Xekouki Evi , King Andy , Thomas Nick , Barazi Sinan , Maratos Eleni , Bullock Peter , Whitelaw Benjamin , Gilbert Jackie , Aylwin Simon

Introduction: In 2017 the term ‘Atypical adenoma’ was removed from the WHO classification, and ‘High-risk adenomas’ was introduced as a term to classify those with rapid growth, radiological invasion, and a high Ki-67 proliferation index. In this retrospective cohort study we have sought to identify the clinical and histological characteristics which are associated with worse outcomes.Methods: Data: We created a dataset of 1793 pa...