Searchable abstracts of presentations at key conferences in endocrinology

ea0035p509 | Endocrine disruptors | ECE2014

Estrogen and bisphenol A affect enamel formation by different signaling pathways

Jedeon Katia , Loiodice Sophia , Marciano Clemence , Lavier Marie-Chantal Canivenc , Berdal Ariane , Babajko Sylvie

Bisphenol A (BPA) is a widespread endocrine disrupting chemical strongly suspected to have adverse health effects. Numerous tissues and cells are affected by BPA, and we showed recently that BPA targets include ameloblasts and enamel. We therefore investigated the effects of BPA on ameloblasts and the possible involvement of the estrogen signaling pathway. Rats were exposed daily to low-dose BPA from the conception to 30 days after birth (30 D). Seventy-five percent of 30 D ra...

ea0032oc2.6 | Bone & Calcium | ECE2013

Hypomineralized teeth as biomarkers of exposure to endocrine disruptors

Jedeon Katia , Molla De La Dure Muriel , Brookes Steven , Marciano Clemence , Canivenc-Lavier Marie-Chantal , Berdal Ariane , Babajko Sylvie

MIH for Molar Incisor Hypomineralization is a recently described pathology affecting around 18% of six year old children. Although a number of putative factors have been hypothesized, etiology of MIH remains unknown. The parallel increase of exposure to endocrine disruptors (EDs) and the prevalence of MIH led us to investigate a possible relationship between both events.Rats were orally exposed daily to low dose of bisphenol A (BPA), genistein, vinclozol...