Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.16.08 | Diabetes and obesity–Clinical obesity and cardiovascular | ECE2015

Vascular and cardiac function in young adults with classical congenital adrenal hyperplasia

Wierzbicka-Chmiel Joanna , Chmiel Artur , Kajdaniuk Dariusz , Marek Bogdan

Background: The patients with classical congenital adrenal hyperplasia (CAH) have increased cardiovascular risk due to the lifelong glucocorticoid therapy and the disease per se.Objective: To evaluate vascular and cardiac function in adults with CAH during optimal corticosteroid and fludrocortisone replacement therapy.Patients and methods: Cross-sectional study of 19 adults with CAH (age 23.7 years ±3.8; males 63%) compared to...

ea0041gp208 | Thyroid - Translational & Clinical | ECE2016

Thyroid hormone profile after the single dose of iodine-containing contrast agent administration during coronary angiography-prospectice study

Rychlik Slawomir , Chmiel Artur , Wierzbicka-Chmiel Joanna , Otremba Lukasz , Kreis Wojciech , Marek Bogdan , Kajdaniuk Dariusz

Introduction: Previous studies suggest close relationship between thyroid morphology and the danger of thyroid hormones (THs) disturbances after high single dose of iodine-containing contrast agent. The aim of the study was to assess the prognostic risk factors which influence on THs after the cardiac catheterization at patient with coronary artery disease (CAD).Methods: One hundred twenty patient (F/M=40/80, 59±11 years old) without recognized prev...

ea0041ep200 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Free triiodothyronine is a predictor factor of left ventricular remodeling in patients after myocardial infarction and primary reperfusion assessed by means of two-dimensional speckle tracking echocardiography

Wierzbicka-Chmiel Joanna , Chmiel Artur , Koloczek Grzegorz , Pifczyk Grzegorz , Marek Bogdan , Kajdaniuk Dariusz

Introduction: Left ventricular remodeling (LVR) is the most important consequence of acute myocardial infarction (AMI). The aim of the study was to assess the value of free triiodothyronine (fT3) in the prediction of LVR after AMI and primary coronary angioplasty (PCI).Methods: Seventy patients (F/M=17/53, 61±11 years old) without recognized previous thyroid dysfunction and AMI were enrolled into the prospective observational study. Conventional and...

ea0035oc9.3 | Reproduction | ECE2014

Late onset hypogonadism influences the endothelial function in men with coronary artery disease

Wierzbicka-Chmiel Joanna , Chmiel Artur , Bienkowski Janusz , Kajdaniuk Dariusz , Marek Bogdan

Late onset hypogonadism (LOH) is common in men with coronary artery disease (CAD) but its interaction with endothelial function and arterial structural changes is debatable.Aim: To investigate whether the LOH in men with CAD predicts endothelial dysfunction.Methods: Two hundred consecutive men with CAD and successful coronary stent implantation or coronary artery bypass grafting were included to the study group (mean age 59±10...

ea0025p110 | Cytokines, growth factors, neuroendocrinology and behaviour | SFEBES2011

Selected adipocytokines serum levels in patients with ischemic stroke

Marek Bogdan , Bienek Radoslaw , Kajdaniuk Dariusz , Nowak Mariusz , Sieminska Lucyna , Glogowska-Szelag Joanna , Kos-Kudla Beata

Adiponectin (ADPN), resistin (RSN) and leptin are proteins that affect insulin resistance and atherosclerosis significantly. Although low levels of adiponectin and high levels of resistin and leptin are associated with coronary heart disease and cardiovascular disease risk factors, it is unclear whether adiponectin, resistin and leptin levels are related to the risk of developing ischemic stroke. The aim of the study was to evaluate the adiponectin, resistin and leptin serum l...

ea0016p293 | Endocrine tumours | ECE2008

The prevalence of chosen complications in 72 acromegalics

Matyja Violetta , Kos-Kudla Beata , Foltyn Wanda , Strzelczyk Janusz , Karpe Jacek , Marek Bogdan , Sieminska Lucyna

Introduction: Hipersecretion of somatotrophin axis hormones in acromegaly favours the development of numerous metabolic and organ complications. The aim of the study was to establish the occurrence integrity of these complications in acromegalics.Material and methods: The tested 72 acromegalics – 32 men aged 46.9±15.2 years and 40 women aged 58.8±12.0 years, for which the period of the illness was determined, the body mass index (BMI) and ...

ea0049ep349 | Endocrine tumours and neoplasia | ECE2017

Parathyroid cancer – clinical presentation, prognostic factors and long-term evolution

Jurecka-Lubieniecka Beata , Michalik Barbara , Bula Grzegorz , Gawrychowski Jacek , Kajdaniuk Dariusz , Marek Bogdan , Tukiendorf Andrzej , Jarzab Barbara

Background: Parathyroid carcinoma (PC) is a rare endocrine malignancy affecting 0.5–5% of all patients with primary hyperparathyroidism. Due to the rarity of PC there is still lack of prognostic implications of the disease and clear consensus regarding management. Our purpose was to evaluate prognostic factors and treatment outcomes of patients treated at the Department of Nuclear Medicine and Endocrine Oncology.Methods: The target group covered 44 ...

ea0037ep995 | Thyroid (non-cancer) | ECE2015

E-selectin in women with autoimmune thyroiditis and the relationships with metabolic syndrome

Sieminska Lucyna , Kos-Kudla Beata , Marek Bogdan , Nowak Mariusz , Kajdaniuk Dariusz , Foltyn Wanda , Walczak Krzysztof , Borowski Artur

Autoimmune thyroiditis (AIT) is characterised by infiltration of the thyroid by lymphocytes and other immune cells. Autoantibodies to thyroid-specific antigens: thyroglobulin (TG) and thyroperoxidase (TPO) are also produced. The penetration of inflammatory cells into target organ is regulated by cytokines and adhesion molecules expressed on thyroid endothelial cells. E-selectin is one of the selectin family, and is responsible for interaction between leukocytes and endothelium...

ea0025p320 | Thyroid | SFEBES2011

Serum homocysteine concentrations in hypothroid, euthyroid and hyperthyroid patients

Kajdaniuk Dariusz , Marek Bogdan , Niedziolka Danuta , Swietochowska Elzbieta , Zeka Gani , Nowak Mariusz , Sieminska Lucyna , Glogowska-Szelag Joanna , Kos-Kudla Beata , Ostrowska Zofia

Background: Thyroid hormone deficiency is associated with increased cardiovascular morbidity, which cannot be fully explained by the atherogenic changes in lipid profile observed in these patients. Hyperhomocysteinemia could help to explain the increased risk for arteriosclerotic coronary artery disease in hypothyroidism because is an important and independent risk factor for cardiovascular disease. Hypothyroidism decreases hepatic levels of enzymes involved in the remethylati...