Searchable abstracts of presentations at key conferences in endocrinology

ea0075a16 | Adrenal gland | EYES2021

An alternative preoperative management of pheochromocytoma

Mourinho Bala Nadia , Guerra Silvia , Maria Aragues Jose , Valadas Cristina

Background: A pheochromocytoma is a rare neuroendocrine tumor, originating from adrenomedullary chromaffin cells. The pre-surgical management of pheochromocytoma is classically performed with alpha-blockers. However, in some cases other pharmacological approaches can be considered.Objective: The aim of the study is to describe the clinical course of patients with pheochromocytoma prepared for surgery with calcium channel blockers (CCB).<p class="abst...

ea0090ep615 | Endocrine-related Cancer | ECE2023

A case report – Should we start breast cancer screening earlier in the MEN-1 patients?

Pina Henrique , Dinis Martins Joao , Duarte Vitoria , Guerra Silvia , Maria Aragues Jose , Valadas Cristina

Multiple endocrine neoplasia type 1 (MEN-1) is characterized by an increased predisposition to the development of tumors of the endocrine tissues, such as parathyroid glands, anterior pituitary, and duodenopancreatic neuroendocrine tumors. It is an autosomal dominant disorder due to germline mutations in the MEN-1 tumor suppressor gene. This gene encodes the menin protein, which is involved in cell growth and differentiation, and in sensing or repairing DNA damage. We present ...

ea0090ep941 | Reproductive and Developmental Endocrinology | ECE2023

Case report - Charge syndrome, a rare entity in the differential diagnosis of primary amenorrhea

Pina Henrique , Dinis Martins Joao , Duarte Vitoria , Guerra Silvia , Maria Aragues Jose , Valadas Cristina

Primary amenorrhea is characterized by the absence of menstruation after the age of 14 without the development of secondary sexual characteristics or after the age of 16 with the development of these. Hypogonadotropic hypogonadism (HH) corresponds to an uncommon etiology of primary amenorrhea. In HH, the differential diagnosis includes Kallmann Syndrome, isolated hypogonadotropic hypogonadism and CHARGE Syndrome. The CHARGE syndrome corresponds to an extremely rare syndrome, w...

ea0049ep1055 | Pituitary - Clinical | ECE2017

Hypogonadotropic hypogonadism in a patient with long-term primary hypothyroidism

Vaz de Castro Raquel , Maria Aragues Jose , Ferreira Florbela , Gomes Vania , Wessling Ana , Joao Bugalho Maria

Abstract: We report the case of a 65-year-old man who presented with erectile dysfunction to an appointment in our Endocrinology department. He referred fatigue, weight gain and constipation as secondary complaints that had been steadily evolving throughout the past 4 years. He denied other symptoms such as visual impairment or headaches as well as the consumption of any medications or drugs. His past medical history was unremarkable. On examination, BMI was 25.8 kg/m2</s...

ea0041ep257 | Clinical case reports - Pituitary/Adrenal | ECE2016

Hypogonadotropic hypogonadism in human immunodeficiency virus infected men: uncommonly low testosterone levels

Coelho Gomes Ana , Maria Aragues Jose , Guerra Silvia , Fernandes Joana , dos Santos Pinheiro Luis , Rui Mascarenhas Mario

Introduction: Hypogonadism is common and occurs prematurely in human immunodeficiency virus (HIV)-infected men, being hypogonadotropic hypogonadism (HH) more frequent. However, HH with very low testosterone has not been described. We present three HIV-infected men with severe HH and normal pubertal development.Case report: Three HIV-infected men, with HIV-1 diagnosis at the ages of 22, 34 and 35 years. Two of them had depressive syndrome, one treated wit...

ea0049ep791 | Endocrine tumours and neoplasia | ECE2017

Polyglandular autoimmune syndrome type III b

Vaz de Castro Raquel , Maria Aragues Jose , Ferreira Florbela , Gomes Vania , Wessling Ana , Tavares Lurdes , Ribeiro Joana , Alves Irina , Camilo Fernandes Afonso , Joao Bugalho Maria

: We report the case of a 57-year-old female diagnosed with Grave’s disease fifteen years before (TSH <0.001 U/ml; FT4 2.3 ng/dl; FT3 7.2 ng/dl, TSAbs 17 U/l). Persistency of hyperthyroidism despite antithyroid therapy led to total thyroidectomy three years after the diagnosis. Thereafter, thyroid function remained normal under hormonal replacement with levothyroxine. The patient had also been diagnosed with Pernicious Anemia at 47 years of age after investigation for...