Endocrine Abstracts

Introduction: Thyroid hormone (TH) replacement therapy in patients with central hypothyroidism (CHT) cannot be reliably guided by TSH levels. Guidelines suggest substitution doses between 1.2–1.6 µg/kg body weight, aiming for free thyroxine levels (fT4) prior to intake in the upper part of normal. However, variability in TH metabolism, concomitant treatments and inaccurate interpretation of TSH levels still puts patients with CHT at risk for inappropriate substituti...

Aim: To investigate the relationship of arterial stiffness with short- and long-term parameters of glycemic control and glycation in patients with type 1 diabetes.Methods: Cross-sectional study at a tertiary care centre including 54 patients with type 1 diabetes free from known CVD. Arterial stiffness was assessed with carotid-femoral pulse wave velocity (cf-PWV). Current level and 10-years history of HbA1c was evaluated, and skin advanced glycation end-...