Endocrine Abstracts

Hormones and other analytes that are requested in the investigation of endocrine abnormalities are routinely measured using automated immunoassays in clinical laboratories. Assay kit inserts usually detail interference in terms of % cross reactivity, but this information is not always communicated to the clinician. Another complicating factor is that different assay platforms show different degrees of interference, therefore clinicians need to be aware of the source of their p...

Background: Polycystic ovary syndrome (PCOS) is a heterogenous condition that affects approximately 12% of females. The diagnosis can be complex and biochemistry tests are routinely relied upon to help identify hyperandrogenaemia and to exclude other conditions. However, although national and international guidelines advocate the use biochemistry tests, little information is provided as to which tests should be used and which other endocrinopathies should be excluded.<p cl...

Background: Diagnosis and treatment guidelines of men with adult-onset testosterone deficiency (TD) were published by the British Society for Sexual Medicine (2017). Laboratory practice has a major role in supporting these with accurate and precise total testosterone (TT) methods and standardised pre- and post-analytical protocols.Objective: Our study investigated whether laboratory practice supported management guidelines of adult-onset TD.<p class=...