Searchable abstracts of presentations at key conferences in endocrinology

ea0018p22 | (1) | MES2008

Primary adrenocortical insufficiency despite a ‘normal’ short synacthen test

Mehta S R , Field B C T , Chaudhri O B , Shaikh H , Morganstein D L , Martin N M , Hatfield E C I , Meeran K

A 60-year-old gentleman who had previously undergone a right nephrectomy for renal cell carcinoma was admitted electively for a left adrenalectomy due to metastatic disease. Prior to this he had been treated with immunotherapy (Sunitinib) and radiotherapy for pulmonary and bony metastases respectively. He was given perioperative cover with hydrocortisone. A short synacthen test (SST) performed the morning after discontinuing hydrocortisone showed a baseline cortisol of 406 nmo...

ea0018p9 | (1) | MES2008

Challenges in the management of Cushing's syndrome in the severely ill patient

Fountain A E C , McGowan B M C , Chaudhuri O , Saha S , Field B C T , Dhillo W , Todd J F , Goldstone A P , Martin N M , Meeran K , Tan T

We present a 57-year-old female with CushingÂ’s syndrome characterised by new type 2 diabetes, hypertension, weight gain, bruising, proximal myopathy and depression. She also had poorly-healing cellulitic ulcers on both legs. Investigations: hypokalaemia and ACTH-dependent CushingÂ’s syndrome. Low dose dexamethasone suppression test: T=0 ACTH 85 ng/l, cortisol 907 nmol/l, T=48 h cortisol 807. High dose dexamethasone suppression test failed to suppr...