Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep502 | Pituitary and Neuroendocrinology | ECE2021

White blood cell count: A potential useful tool for suspected Cushing’s syndrome

Merlo Ignacio , Paja Miguel , Martinez Adela , Monzon Andoni , Rodriguez Josune

BackgroundSuspicion of Cushing´s syndrome (CS) is usually suggested by non-specific clinical data. Chronic hypercortisolism associates changes in white blood cell count (WBC), essentially a higher count with relative lymphopenia. Our purpose is to investigate the prevalence of these findings among a local series of patients with CushingÂ’s syndrome before and after the hypercortisolism revertion to assess the diagnostic value of these parameters...

ea0063p396 | Thyroid 1 | ECE2019

Is detection of braf mutation enough to decide prophylactic central neck dissection (CND)?

Paja Miguel , Exposito Amaia , Arrizabalaga Cristina , Martinez Adela L , Monzon Andoni , Oleaga Amelia

Introduction: Most recent ATA thyroid nodule/DTC guidelines recommend thyroidectomy without prophylactic CND for small (T1 or T2), non-invasive, clinically node-negative PTC (cN0). However, some studies have suggested an association between the BRAFV600E mutation and the risk of nodal disease. Moreover, BRAF V600E mutation have recently showed significant association with recurrence in solitary intrathyroidal PTC between 2 and 4 cm (pT2) making suitable a more aggressive treat...

ea0063p386 | Thyroid 1 | ECE2019

Evaluation of the diagnostic algorithm when a suppressed tsh is found in the laboratory

Paja Miguel , Monzon Andoni , Martinez Adela L , de la Prieta M Concepcion , Aguayo Francisco J , Lizarraga Aitzol , Oleaga Amelia

Introduction: Abnormal thyroid function is the most common disease in endocrinology and its screening of made by plasmatic (TSH), followed by (fT4) determination if abnormal. (fT3) determination is only used when pathological (TSH) and normal (fT4) are found, even if there is no evidence supporting this procedure, apart from the greater technical difficulty of measuring (fT3) due to its lower plasma concentration.Material and Methods: Observational retro...

ea0063p89 | Calcium and Bone 1 | ECE2019

Diagnostic and treatment delay in primary hyperparathyroidism (phpt): a pending issue

Paja Miguel , Martinez Adela L , Monzon Andoni , Arrizabalaga Cristina , Zabalegui Alba , Iglesias Natalia C , Calles Laura A , Etxeberria Eider M , Gutierrez Teresa

Background: PHPT is the leading cause of hypercalcemia in outpatients. Its clinical presentation varies from asymptomatic forms to renal or bone complications. The only curative treatment is surgical resection, and delayed diagnosis can lead to serious morbidity.Objective: Identify the presence of PHPT at least one year prior to referral to endocrinology consultation. Secondly, determine whether diagnostic delay leads to increased complications.<p cl...

ea0063p369 | Thyroid 1 | ECE2019

Impact of thyroid autoimmunity on obstetric and perinatal outcomes in pregnant women with subclinical hypothyroidism

Oleaga Amelia , Jimenez-Telleria Patricia , Goni Fernando , Moreno Cristina , Arrizabalaga Cristina , Izuzquiza Ana , Espiga Javier , Martinez Adela , Zabalegui Alba , Paja Miguel

Introduction: Maternal clinical thyroid disorders can cause reproductive complications. However, the effects of mild thyroid dysfunction are controversial. The impact of SH and thyroid autoimmunity on miscarriages, obstetric and perinatal outcomes are not yet well established and the effect of levothyroxine replacement in pregnant women with SH is unclear. The aim of this study was to evaluate the impact of thyroid autoimmunity in early pregnancy on obstetric and perinatal out...

ea0063p405 | Thyroid 1 | ECE2019

Radiofrequency ablation in the treatment of benign thyroid nodules: a good alternative to surgery

Moreno Cristina , Paja Miguel , Izuzquiza Ana , Espiga Javier , Arrizabalaga Cristina , Martinez Adela Leyre , Monzon Andoni , Zabala Rosa , Iglesias Natalia , Calles Laura

Introduction: To date, benign thyroid nodules complainig of symptomatic or cosmetic problems and autonomous functioning thyroid nodules (AFTN) have generally been treated with surgery or I131. Radiofrequency ablation (RFA) is a novel technique that has demonstrated safety and efficacy in the treatment of these nodules. We describe the clinical experience at our hospital.Material and method: We include 33 patients (28 women, 5 men) from January 2013 to Se...

ea0070aep142 | Bone and Calcium | ECE2020

The prevalence of postoperative (PO) chronic hypoparathyroidism (HypoPTH) in bilbao, northern spain

Oleaga Amelia , Goñi Fernando , Moreno Cristina , Iglesias Natalia , Calles Laura , Monzon Andoni , Martinez Adela , Merlo Ignacio , Gutierrez Teresa , Ruiz de Velasco Elena , Paja Miguel

Introduction: HypoPTH is an uncommon disorder, mostly due to anterior neck surgery. The prevalence of HypoPTH has been studied in surgical series and registries, (USA, Denmark and Hungary) where only a minority of patients has HypoPTH due to non-surgical causes. In Spain data on PO HypoPTH in endocrinologist clinical practice has been published recently. The aim of this study was to establish the prevalence of chronic PO HypoPTH in Bilbao area, with a population 2019: 346,843....

ea0056p1156 | Thyroid cancer | ECE2018

Diagnostic accuracy of CNB in tyroid nodules smaller than 1 centimeter

Paja Miguel , Ugalde Aitziber , Korta Igone , Zabala Rosa , Martinez Adela L , Zabalegui Alba , Arrizabalaga Cristina , Calles Laura A , Etxebarria Eider , Del Cura Jose L

Current guidelines suggest sonographic follow-up in thyroid nodules smaller than 10 mm with intermediate or highly suspicious features as ultrasound-guided FNAC has poor results in these nodules, and the risk of non-diagnosed thyroid carcinoma is very low. CNB has proved superior to repeated FNAC in case of insufficient or indeterminate first FNAC.Objective: Evaluate diagnostic accuracy of CNB in nodules smaller than 10 mm with intermediate or high suspi...

ea0056p1157 | Thyroid cancer | ECE2018

Serum thyroglobulin (sTg) before surgery in euthyroid patients with differentiated thyroid cancer (DTC)

Paja Miguel , Lizarraga Aitzol , Exposito Amaia , Teresa Gutierrez M , Barrios Borja , Iglesias Natalia C , Zabalegui Alba , Arrizabalaga Cristina , Martinez Adela L , Oleaga Amelia

sTg is universally accepted as the best marker of disease status in DTC. Its presurgical serum level may suggest the presence of distant metastasis in case of very high level, but the correlation between its level and the characteristics of the tumour is yet to be defined.Objective: To evaluate preoperative thyroglobulin as predictor of DCT features.Methods: Preoperative sTg was measured in patients operated for DTC between 2011&#1...