Searchable abstracts of presentations at key conferences in endocrinology

ea0014p379 | (1) | ECE2007

Association of p53 codon 72 polymorphism with thyroid cancer

Caglayan Sinan , Aral Cenk , Massaumilary Sirin , Ozisik Gokhan , Baloglu Huseyin , Akkiprik Mustafa , Ozer Ayse , Ozata Metin

Tumors of thyroid gland are one of the most prevalent forms of human cancers. Despite the various molecular mechanisms, mutations or polymorphisms of p53 have a potential role in the development and/or progression of human malignancies including thyroid. A common variation in p53 that results in adenine to proline change in codon 72 has been identified as a predisposing factor for various cancers since controversial results have been reported. In this study, we investigated co...