Searchable abstracts of presentations at key conferences in endocrinology

ea0065p133 | Endocrine Neoplasia and Endocrine Consequences of Living with and Beyond Cancer | SFEBES2019

Tumour detection and outcomes of surveillance screening in SDHB and SDHD mutation carriers

White Gemma , Masucci Michael , Anandappa Samantha , Joshi Mamta , McGowan Barbara , Obholzer Rupert , Jacques Audrey , Christodoulou Dimitra , Izatt Louise , Velusamy Anand , Carroll Paul

Background: Pathogenic variants in genes encoding Succinate Dehydrogenase subunits B and D (SDHB/SDHD) predispose to Phaeochromocytoma and Paraganglioma (PPGL). Cascade genetic screening identifies relatives at risk and allows surveillance screening to enable early detection of PPGLs.Methods: Retrospective analysis of genetic databases and hospital records between January 2000 and December 2018 identified relatives carrying SDHB and <em...