Searchable abstracts of presentations at key conferences in endocrinology

ea0094oc6.6 | Metabolism, Obesity and Diabetes | SFEBES2023

Low carbohydrate diets in Type 1 diabetes – defining the degree of glycaemic control and nutritional ketosis

Ozoran Hakan , Karpe Fredrik , Dyson Pam , Tan Garry , Matheou Michael

Background: Carbohydrate-restricted diets in type 1 diabetes mellitus (T1DM) are highly controversial. A commonly held concern is that a low carbohydrate diet may more readily result in conversion to diabetic ketoacidosis – one of the most severe complications of poorly managed T1DM. Of note, there is no clear evidence for this phenomenon. We evaluated metabolic profiles in patients with T1DM who had self-selected carbohydrate-restricted diets.<p clas...

ea0091p28 | Poster Presentations | SFEEU2023

Mitochondrial DNA Depletion syndrome 1 (MNGIE type) – a rare cause of premature ovarian failure?

Matheou Michael , Tan Garry D , Karpe Fredrik , Brady Stefen , Kent Louisa , Javaid Kassim , Marshall Jonathan , Shears Deborah , Turner Helen E

Case history: A 39 year old lady was being investigated and managed for premature ovarian insufficiency (onset aged 29y) associated with an unusual constellation of symptoms. Following normal childhood and pubertal development, she subsequently developed fatigue, multiple gastrointestinal symptoms and was underweight with evidence of weight loss, and a most recent BMI of 17 kg/m2. She had previously been reviewed due to marked absence of subcutaneous fat in the lowe...

ea0104p161 | Neuroendocrinology | SFEIES24

Challenges of treatment of metastatic insulinoma- case series

Apsara Dilrukshi Mathara Diddhenipothage Shani , Matheou Michael , Wilson Shaun , Moore Niall , May Christine J. H. , Jafar-Mohammadi Bahram

Introduction: Marked heterogeneity has been noted in clinical phenotypes of metastatic insulinomas. We present a case series highlighting heterogenous clinical presentations, radiological features, and treatment modalities.Case-1: 55 Male, chronic diarrhoea, weight loss of 18months, with severe hyper-insulinemic hypoglycaemia (HH) of few weeks. 37 mm pancreatic body tumour with multifocal liver metastases; one with marked peri-lesional steatosis (PS). Gr...