Searchable abstracts of presentations at key conferences in endocrinology

ea0026p625 | Clinical case reports | ECE2011

Testicular microlithisis: how worried should we be?

Matos M J , Freitas P , Carvalho D

Introduction: Gynecomastia is a relatively common reason for consultation, with a high prevalence in the neonatal period, puberty and with aging. The diagnostic approach should be more thorough in normal-weight individuals with recent onset of gynecomastia, rapid growth of breast tissue, or in the setting of a large painful breast. Besides the evaluation of liver function, testosterone, estradiol, LH and β-hCG, testicular ultrasound evaluation is important to exclude test...

ea0029p100 | Adrenal cortex | ICEECE2012

Exogenous corticosteroids: guilty or innocent?

Matos M. , Freitas P. , Belo S. , Frazao J. , Pimenta T. , Guimaraes S. , Carvalho D.

Introduction: The association between autoimmune diseases, including systemic lupus erythematosus (SLE), and endogenous hypercortisolism is rare. The latter is usually misinterpreted as iatrogenic in the case of patients taking exogenous systemic corticosteroid therapy. The excess endogenous glucocorticoids may play an important role in suppressing autoimmune activity. Similarly, the abrupt resolution of endogenous hypercortisolism may lead to a rebound worsening of autoimmuni...

ea0026p626 | Clinical case reports | ECE2011

Virilizing ovarian steroid cell tumor: clinical case

Matos M J , Freitas P , Costa M A , Paiva V , Guimaraes M , Lopes J M , Carvalho D

Introduction: Androgen-producing tumors are a rare cause of hyperandrogenism (±0.2%). Ovarian steroid cell tumors represent <0.1% of all ovarian tumors. They may present at any age and in 12–50% of cases are associated with virilization. The majority of these tumors are benign or low-grade malignanies.Clinical case: A 74-year-old female patient, with history of vaginal hysterectomy for genital prolapse at the age of 50, is referred to Endoc...

ea0029p396 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Central diabetes insipidus: about two clinical cases

Nogueira C. , Matos M. , Esteves C. , Jorge G. , Couto J. , Neves C. , Queiros J. , Vinha E. , Bernardes I. , Carvalho D.

Introduction: Central diabetes insipidus (CDI) is produced by the destruction of the magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei which results in decreased arginine vasopressin (AVP) synthesis and secretion.Case report 1: Forty-five year old female, previously healthy, was observed in April 2011 complaining of polydipsia, polyuria, nocturia and weight loss since January. Diabetes mellitus (DM) was excluded and she was ...

ea0016p153 | Clinical cases | ECE2008

Hypoglycaemia following gastric banding

Oliveira A , Freitas P , Matos M , Vinha E , Braga D , Maia J , Bartosch C , Exposito M , Medina J

Introduction: Recently, noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) has been described following Roux-en-Y Gastric Bypass Surgery in morbidly obese patients. It has been proposed that hypoglycaemia might be a consequence of a failure to adaptively decrease insulin secretion after surgery. The authors present a case of a morbidly obese patient with severe hypoglycaemias beginning 3 months after gastric banding surgery.Case report: A 60-ye...

ea0029p799 | Endocrine tumours and neoplasia | ICEECE2012

Neuroendocrine Tumor with Clinical Characteristics of Insulinoma

Menezes J. , Rodrigues E. , Nogueira C. , Esteves C. , Jorge G. , Matos M. , Graca L. , Pinheiro J. , Pinheiro Loureiro , Lopes J. , Costa J. , Costa Maia , Carvalho D.

Introduction: Insulinomas are almost always located in the pancreas and are usually small. The peak incidence is from the third to fifth decade of life, with females being slightly more frequently affected. The average duration of neuroglycopenic symptoms prior to diagnosis is often prolonged, being more than 5 years in 20% of patients.Case presentation: Female, 52 years old, medical history notable for hypertension, dislipidemia and Graves disease. She ...

ea0026p403 | Thyroid (non cancer) | ECE2011

Thyroid nodules in children: review of 67 patients

Mesquita J , Lima S Paco , Matos M J , Neiva F , Pauperio S , Martins S , Costa C , Correia C Castro , Carvalho Davide , Fontoura Manuel

Introduction: Thyroid nodules in children and adolescents are less prevalent, but entail greater risk of malignancy than in adults. Most are asymptomatic because they are associated with normal thyroid function, but their prevalence is increasing due to the incidental diagnosis by neck ultrasound.Aims: To evaluate the characteristics of a pediatric population with thyroid nodules submitted to fine-needle aspiration (FNA) biopsy.Met...

ea0026p699 | Diabetes complications | ECE2011

Gilbert syndrome and diabetes: a perfect union?

Matos M J , Souto S B , Oliveira A I , Silva S , Vinha E , Freitas P , Queiros J , Braga D C , Carvalho D

Introduction: Gilbert syndrome is one of the most common inherited diseases, with a prevalence of 5–7%. It is caused by a mutation in UGT1A1 gene, which is in turn responsible for a deficiency in bilirubin glucuronidation. It courses with unconjugated hyperbilirubinemia, and jaundice may occur in adolescence, after fasting, exercise, or in menses, and also with certain drugs. Individuals with Gilbert syndrome seem to have a reduction in the prevalence of micro- and macrov...

ea0026p720 | Diabetes (epidemiology, pathophysiology) | ECE2011

Diagnostic criteria for glucose homeostasis abnormalities in obese patients: are there any differences?

Mesquita J , Rodrigues P , Nogueira C , Belo S , Esteves C , Matos M J , Varela A , Freitas P , Queiros Joana , Correia Flora , Oliveira Bruno , Ferreira de Almeida Manuel , Guimaraes Joao Tiago , Medina Jose Luis , Carvalho Davide

Introduction: The course of type 2 diabetes mellitus (DM) is insidious and, before its development, other glucose homeostasis abnormalities can be detected: impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and elevation of HbA1c.Aims: To compare the prevalence of glucose homeostasis abnormalities in obese patients, using diagnostic criteria of American Diabetes Association (ADA) 2009, ADA 2010 and International Diabetes Federation (IDF) 2...