Endocrine Abstracts

Introduction: De Morsier described an association between optic nerve hypoplasia and an absent septum pellucidum in 1956, termed septo-optic dysplasia. SOD is a common cause of multiple pituitary hormone deficiency in children. Clinical features can evolve. Genetic mutations in regulators of pituitary development have been suggested.Aims: To determine associated endocrinopathies, ophthalmological and radiological findings in an Irish paediatric cohort of...

Aims: Childhood obesity is reaching epidemic proportions. Obesity may be primary (obesogenic environment), secondary (hormonal imbalance, drugs), monogenic (POMC) or be part of a complex phenotype-genetic obesity syndromes. It is important to distinguish between classifications. Our aim was to review our cohort of ‘obese’ patients with this in mind.Methods: Patients referred to our Paediatric Endocrinology Service specifically for management of...