Endocrine Abstracts

Multiple endocrine neoplasia type 2 (MEN2) is a rare hereditary autosomal dominant syndrome, caused by activating germline mutations in the RET proto-oncogene. Medullary thyroid carcinoma (MTC) remains the most common and aggressive manifestation of MEN2. The family case of MEN 2 syndrome in Belarussian population is analyzed. During the analysis of the records of clinical case of patient’s death in the reginal hospital because of thrombosis of mesenteric vessels and acut...

Introduction/Aim: The incidence of type 2 diabetes in Belarus continues to grow. Alongside with the standard treatment search for the new methods of intervention still continued. Whole body cryotherapy appears to be a promising method of metabolic correction. Study aim was the estimation of various low-temperature regimen influence on biochemical parameters and BMI characteristics of patients with metabolic syndrome and type 2 diabetes and selection the optimal low-temperature...

Introduction: Today, thyroid papillary cancer remains to be the most frequent diagnosed malignancy. Despite highly positive outcomes, treatment protocol still requires surgical intervention, which, in turn often affects not only thyroid and regional lymph nodes, but also recurrent nerve and parathyroid glands. The aim of our study was to compare the metabolic compensation of calcium and thyroid metabolism improvement in patients operated on thyroid cancer recently and 20 years...

Hyponatremia - a decrease in serum sodium to 135 mmol/l or less can lead to serious complications. In patients with various pathologies and serum sodium levels of 120–125 mmol/l mortality reaches 23%, in levels less than 115 mmol/l - 50%. Biochemical verification of hyponatremia is not difficult. It is difficult to establish the cause and treatment of chronic hyponatremia. Patient S., 64 years old, was hospitalized in a state of alcoholic intoxication with a diagnosis of ...

Obesity and weight excess is a widespread condition all over the world, as well as thyroid nodular disease. Screening studies in different populations prove a higher frequency of nodular thyroid formations of various nature in overweight individuals.Aim: In our study, we evaluated the dynamics of the volume of dominant and non-dominant nodular formations, as well as their sonographic structure in overweight patients with prediabetes in the groups with tw...

Introduction: Multiple endocrine neoplasia type 1 (MEN-1) is a rare, autosomal dominant inherited disorder, characterized by a high predisposition to develop a wide spectrum of endocrine and nonendocrine tumors, mostly of parathyroids, endocrine pancreas, and anterior pituitary.Methods: Analysis of clinical and laboratory data, family history of multiple endocrine neoplasia.Results: A 19-year-old woman with autoimmune thyroiditis a...

A lot of new data have been recently generated regarding the complex relationship between the thyroid function and metabolic parameters.The aim of the study was to estimate the obesity and metabolic syndrome (MS) rates according to the age and the thyroid function in the residents of Belarus.We have examined 894 subjects aged 18–44 years (82.2% females) living in Stolin district, Brest region of Belarus. The endocrinological e...

Introduction and backgroundAccording to world diabetes-focused organizations (EASD and IDF) the number of patients with type 2 diabetes mellitus (T2DM) and obesity is increasing tremendously all over the world. The FTO gene (Fat mass and obesity-associated gene) was noticed during GWAS-study at 2007, when it’s multiple polymorphic variants were detected, many of which were associated with obesity and T2DM. Significant differences in allele prevalenc...

Introduction & BackgroundA COVID-19 pandemic smashed the world not only by it`s severity, but also by the tremendous amount of comorbidities, many of them having autoimmune basis. Thyrotoxicosis as one of the above - could result either from SARS-CoV-2 directly infecting the thyroid gland, as described in other viral infections, or can develop due to immune overactivation during the severe viral load. Subacute thyroiditis (SAT) is a self-limiting inf...