Endocrine Abstracts

I hope to be able to offer some advice and guidance having only recently attained my consultant post last year. The decision of where you are going to start your consultant career is potentially the largest decision you have made regarding your career to date. So, how can you prepare yourself to stand the best chance against other competitors in the field? By breaking the process down I will cover the following areas-– The benefits of trying to opti...

As a specialist trainee nearing the end of training in endocrinology and diabetes I will share my experience and thoughts about specialty training and a career in endocrinology.If you are wondering why to choose endocrinology and diabetes as a specialty, what the specialty has to offer you, what you will experience as a specialty trainee and how to make the most out of your training program, then this presentation is designed with you in mind.<p clas...

Case history: 20 year old man with a complex cardiac history of Shone’s syndrome, out of hospital cardiac arrest 2015 (CRT-D implant) and multiple previous episodes of fast atrial fibrillation was admitted to hospital (28/11/2019) with 3 weeks history of intermittent palpitations and shortness of breath. His regular medications included amiodarone and bisoprolol. Examination revealed a fine tremor of outstretched hands, no obvious goitre or thyroid eye disease. Thyroid functio...

A 33-year-old patient with background of Bilateral achilles tendonitis, was referred to Endocrinology with raised IGF-1 and concern of acromegaly. Her symptoms included arthralgias and change in hand and feet size. Pituitary profile confirmed elevated IGF-1 181 nmol/l, otherwise normal pituitary profile. On OGTT, there was failure to suppress Growth hormone. Pituitary MRI revealed large macroadenoma with suprasellar extension, extension into right cavernous sinus with optic ch...

A 28-year-old female presented with oligomenorrhoea and bilateral headaches in 2018. Initial blood testing revealed raised prolactin, prompting further assessment of pituitary function. This showed a high IGF-1(132 nmol/l), subsequent oral glucose tolerance test confirmed the diagnosis of acromegaly. It is worth noting that she did not exhibit many of the typical clinical features of acromegaly. MRI demonstrated a left-sided pituitary macroadenoma invading the cavernous sinus....

Introduction: This case report described a patient who presented with medullary thyroid carcinoma (MTC) requiring a total thyroidectomy and radial neck dissection. Genetic testing performed in the context of MTC revealed RET proto-oncogene mutation. Baseline screening identified bilateral pheochromocytomas requiring treatment with bilateral adrenalectomy. Case report: 60-year-old male patient presented with a neck lump which had been present for few year...

A 63-year-old woman with a history of bipolar disorder and hypothyroidism under section 3 of the Mental Health Act in a psychiatric centre was admitted with severe hypothermia, bradycardia, hypotension and decreased GCS. She was on procyclidine and haloperidol for bipolar disorder and on intravenous antibiotics for 2 days for recurrent cellulitis in her leg. She was on levothyroxine 50 μg daily but was non compliant with her medications.Thyroid func...

Case history: A 39 year old female presented reporting a 5-year history of swollen face, hands and feet, with associated joint pain. She was initially investigated for rheumatoid arthritis. She had no significant past medical history except for a previous miscarriage in 2014 and treatment for hypertension in a subsequent successful pregnancy. Post-partum she breastfed with no difficulty for 18-months but remained amenorrhoeic during this time. During 2016 she noticed increase ...

Succinate dehydrogenase (SDH) mitochondrial enzyme complex mutations are associated with hereditary paragangliomas and phaeochromocytomas. Of late, there has been more awareness of the development of other tumours in this patient cohort. There is limited evidence of propensity for development of Prolactinomas and other pituitary tumours in patients harbouring mutations in the SDH complex genes. We present three cases attending our center with a diagnosis of prolactinoma and <e...

Hypertension is the most commonly recognised cardiac manifestation of a phaeochromocytoma. There are however a variety of other cardiac presentations including arrhythmias and the increasingly reported Takotsubo cardiomyopathy. We present the case of a female patient presenting acutely to the general medical take who was found to have cardiac arrhythmias and transient left ventricular dysfunction.The initial presentation was breathlessness, chest pain, s...