Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep79 | Adrenal and Cardiovascular Endocrinology | ECE2020

Endothelial vascular adrenal cyst with unusual presentation

Lichewitz Gavriel , Pal Marina , Karine Atlan , Mazeh Haggi

Primary adrenal cysts are a relatively rare form of lesions with incidence of 0.06% in general population and higher prevalence in women (female-to-male ratio 2.3:1). Adrenal endothelial cysts are the most common form of adrenal cysts subtypes (45%) and they usually present with abdominal or flank pain, or nonspecific symptoms . Adrenocortical carcinomas are a rare condition as well, with an incidence of 1–2 per million per year. The typical clinical presentation may inc...

ea0063p50 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

A seminoma with entrapped nerve ganglion masquerading as a paraganglioma

Rosenblum Rachel Chava , Atlan Karine , Diment Judith , Mazeh Haggi , Rotman-Pikielny Pnina , Twito Orit

Background: The differential diagnosis of retroperitoneal tumors includes lymphoid, germ cell and neurogenic tumors such as paraganglioma. Paragangliomas are rare neuroendocrine tumors of the autonomic nervous system, which may secrete catecholamines and their metabolites. Clinical features include sustained or paroxysmal hypertension, headaches, sweating and palpitations. Here we present an unusual case of a retroperitoneal tumor entrapping a sympathetic nerve ganglion and mi...

ea0081oc14.6 | Oral Communications 14: Late Breaking | ECE2022

Engaging the Endocannabinoid System in Neuroendocrine Neoplasms (NENs) potentiates treatment outcomes and null drug resistance

Avniel- Polak Shani , Polak David , Oleinikov Kira , Gross David J , Wald Ori , Izhar Uzi , Mazeh Haggi , Drier Yotam , Glasberg Simona

Introduction: Patients with unresectable NENs are offered a variety of non-curable therapeutic options, which eventually fail due to drug resistance. Increasing evidence suggest an anticancer trait of cannabinoids, via cellular pathways including mTOR, known to be associated with drug resistance development. Still, limited data exist on the anti-cancer effects of cannabinoids in NENs.Aims: To understand the possible anti-tumor role of the cannabinoids an...

ea0049ep1374 | Thyroid (non-cancer) | ECE2017

Trends in the clinicopathological features and clinical outcomes of medullary thyroid carcinoma – an Israeli multicenter study

Hirsch Dania , Twito Orit , Levy Sigal , Bachar Gideon , Robenshtok Eyal , Gross David J , Mazeh Haggi , Benbassat Carlos

Background: The massive use of neck sonography has led to a dramatic increase in the incidence of thyroid cancer detection, predominantly small papillary carcinomas. However, changes in the presentation and course of medullary thyroid carcinoma (MTC) over time remain unclear.Objective: To evaluate trends in the presentation and outcomes of MTC.Methods: Patients treated for MTC at four medical centers in Israel were divided into two...

ea0063gp14 | Adrenal and Neuroendocrine - Tumour | ECE2019

Endoscopic ultrasound guided radiofrequency ablation (EUS-RFA) as a novel therapeutic approach in highly-selected pancreatic functioning and non-functioning neuroendocrine neoplasms (pNENs) patients: Preliminary report

Oleinikov Kira , Dancour Allain , Epshtein Julia , Benson Ariel , Mazeh Haggi , Tal Ilanit , Livovsky Dan , Goldin Eran , Gross David J , Jacob Harold , Grozinsky-Glasberg Simona

Introduction: EUS-RFA is rapidly emerging as a possible treatment alternative for patients with pNENs who are poor surgical candidates.Aim(s): To summarize our experience in terms of feasibility, safety and efficacy of EUS-RFA in a cohort of patients with functional and non-functional pNENs.Materials and methods: Retrospective case series of pNENs patients treated with EUS-RFA at two tertiary referral centers in Israel between Marc...