ea0098o2 | Other | NANETS2023
Mohindroo Chirayu
, Baydogan Seyda
, Agarwal Parul
, Laheru Dan
, Wright Robin
, Prakash Laura R.
, Mork Maureen E.
, Klein Alison P.
, Maxwell Jess
, H.G. Katz Matthew
, Dasari Arvind
, Kim Michael P.
, He Jin
, McAllister Florencia
, De Jesus-Acosta Ana
Background: 10% of pancreatic neuroendocrine tumors (pNETs) are thought to be related to inherited syndromes, (MEN1, MEN4, VHL, NF1 and TSC). Growing evidence suggests, that clinically sporadic appearing pNETs can harbor germline mutations. Here, we report the prevalence of pathological/likely pathological germline variants (P/LP) in 2 cohorts: 1) High-risk and 2) Unselected.Methods: We retrospectively collected clinical data of pNET patients seen at MD ...