Endocrine Abstracts

Chronic ulcers represent very common and serious complications of diabetes mellitus. Their persistence leads to repeated infections, often leading to amputation. The current state-of-the art treatment includes debridement which is aimed at preparing the wound bed and stimulating ulcer edges to trigger tissue regeneration. We aimed to test the hypothesis that features of the debrided tissue may be indicative of the natural evolution of the wound. As a first step for this charac...

Introduction: Alterations in the hypothalamic–pituitary–thyroid axis have been reported following GH replacement, with a decline in circulating T4 concentration the most consistent finding. However, the clinical significance of GH-induced alterations in circulating levels of thyroid hormone is unclear.Aim: To examine the relationship between changes in serum concentration of thyroid hormones and known biological markers of thyroid ho...