Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep1300 | Late Breaking | ECE2024

Thyroid cyst infected with capnocytophaga canimorsus

Cadogan Sinead , McQuaid Siobhan

Infected thyroid cysts are a rare complication of the thyroid gland, with haematogenous spread from a distal site of infection believed to be one mechanism of infection. We report the case of a patient who presented with an infected thyroid cyst due to Capnocytophaga canimorsus bacteraemia after sustaining a dog bite on her hand. A 37-year-old female presented to the Emergency Department with a five-day history of fevers, neck pain, and a rapidly enlarging neck swelling. The p...

ea0037ep607 | Obesity and cardiovascular endocrinology | ECE2015

Audit of metabolic profiles in women with Turner syndrome

Kyithar Ma Pyeh , McQuaid Siobhan

Introduction: Adults with Turner syndrome (TS) are at increased risk of cardiovascular morbidity and mortality. The aim of this study was to evaluate the compliance with clinical guidelines (Bondy 2007) in measuring metabolic profiles in adults with TS.Methods: Case notes of patients attending a dedicated TS clinic were studied. Variables assessed included anthropometric measurements, blood pressure (BP), fasting plasma glucose (FPG), HbA1c, fasting lipi...

ea0056p893 | Clinical case reports - Thyroid/Others | ECE2018

A testicular mass in a patient with Klinefelter syndrome

Newman Aoife Christine , McQuaid Siobhan

A 35 year old gentleman with a history of 47 XXY Klinefelter Syndrome (KS) and previous orchidopexy presented to the endocrine service with a two-week history of left sided testicular pain. Examination revealed a tender left testicle. Testicular ultra-sound confirmed bilateral atrophic testes and a 5 mm hypoechoic lesion in the left upper pole. This patient presented with KS at the age of 15 years with gynaecomastia and elevated gonadotrophins. After urgent urological review a...

ea0056p929 | Female Reproduction | ECE2018

A retrospective analysis of the audiometric data of a cohort with turner syndrome

Newman Aoife Christine , McQuaid Siobhan

Turner Syndrome (TS) is a multi-systemic genetic condition in females caused by partial or complete deletion of one X chromosome. It affects approximately 25-50 per 100,000 live births. Recent data shows that up to 60% of patients with TS will experience recurrent otitis media and 30% will suffer permanent hearing impairment. International guidelines recommend audiometric screening at diagnosis, every three years in childhood and at least every five years in adulthood for TS p...

ea0081p726 | Thyroid | ECE2022

Graves’ eye disease associated with SARS-CoV2 infection

Noble Jane , Carthy Brian , McQuaid Siobhan

Introduction: SARS-CoV2 infection or vaccination against SARS-CoV2 has been linked to the onset or recurrence of Autoimmune and subacute thyroiditis resulting in thyroid dysfunction.Case: We describe a case of Thyroid eye disease temporally associated with SARS-CoV 2 infection in a 48 year old female with a one-year history of subclinical hypothyroidism without interval thyroid hormone replacement or SARS-CoV2 vaccination. Two months following PCR confir...

ea0049ep1318 | Thyroid (non-cancer) | ECE2017

TRAB positive thyroid dysfunction associated with Alemtuzumab treatment for MS: A case series

Garrahy Aoife , Ali Sulaiman , McQuaid Siobhan , Byrne Maria M

Alemtuzumab is a monoclonal antibody directed against CD52 licenced for the treatment of relapsing remitting multiple sclerosis (MS). Thyroid dysfunction occurs in one third of patients, likely secondary to lymphocyte reconstitution.Case 1: A 36 year old female, treated with alemtuzumab 15 months prior, presented to antenatal clinic at 12 weeks gestation with symptoms of thyrotoxicosis. fT4 was 83.7 pmol/l (RR 12-22), TSH suppressed, TRAB positive. She w...

ea0021p150 | Diabetes and metabolism | SFEBES2009

Diabetic ketoacidosis: a 5-year retrospective analysis

O'Shea Triona , Healy Marie Louise , Nolan John , McQuaid Siobhan

Introduction and methods: Despite advances in diabetes treatment, diabetic ketoacidosis (DKA) remains a significant cause of morbidity. We performed a 5-year retrospective analysis of DKA episodes (2004–2008). Results were compared with an earlier study (1997–2001).Results: Ninety-four episodes of DKA (defined as hyperglycaemia, ketosis and acidosis) were identified through Hospital Inpatient Enquiry (HIPE). Patients with Type 1 diabetes mellit...

ea0073aep552 | Pituitary and Neuroendocrinology | ECE2021

A complex case of refractory hypercalcaemia, end-stage diabetic nephropathy with pituitary mass and hypopituitarism– is there a unifying diagnosis?

Fennell David , Holland John A , Corkery Laura , Ludgate Stephen , McQuaid Siobhan

A 54-year-old female presented with one week of weakness, fatigue, headache, worsening constipation, and general malaise. Background history included long-standing type 1 diabetes (glutamic acid decarboxylase positive), on continuous subcutaneous insulin infusion, proliferative diabetic retinopathy, end-stage diabetic nephropathy on haemodialysis and subclinical hypothyroidism. Tertiary hyperparathyroidism was diagnosed (adjusted calcium 2.82 mmol/l, phosphate 1.42 mmol/l, par...

ea0073aep728 | Thyroid | ECE2021

A case of Graves’ disease (GD) associated with HIV disease and late immune reconstitution inflammatory syndrome (IRIS) following initiation of antiretroviral therapy (ART)

Ludgate Stephen , P Connolly Stephen , Fennell David , McQuaid Siobhan

GD following ART occurs rarely, in 3% of HIV-infected women1. It is suggested that CD4 cells increase in a biphasic pattern following ART initiation, with the expansion of naïve CD4 cells following months after the initial redistribution of memory CD4 cells from lymphoid tissue2. A 40-year-old Brazilian lady was diagnosed with HIV in late 2016 following admission with cryptococcal meningitis and salmonellosis, requiring treatment with anti-fungal age...

ea0050p391 | Thyroid | SFEBES2017

Iodine status on the Island of Ireland

Mullan Karen , McKeever Edward , Hamill Lesley , Doolan Katie , Young Ian , Smyth Peter , Flynn Albert , Patterson Chris , Walton Janette , Meharg Andy , Graham Una , McMullan Paul , McCance David , Bell Marcia , McHugh Cathy , McQuaid Siobhan , Tuthill Antoinette , Black Neil , O'Loughlin Aonghus , Woodside Jayne

Iodine is a trace element required for thyroid hormone production. Requirements increase in pregnancy, when even mild deficiency may affect offspring neurocognitive development.The gold standard for assessing iodine status is population surveys of urinary iodine concentration (UIC). The WHO also suggests a population prevalence of >3% of TSH values > 5 mIU/L indicates deficiency. A recent UK survey of 700 teenage girls demonstrated ...