Searchable abstracts of presentations at key conferences in endocrinology

ea0063p751 | Thyroid 2 | ECE2019

Differences between EU and ACR TI-RADS in identifying potential malignant thyroid nodules

Icin Tijana , Bajkin Ivana , Simeunovic Jovana Prodanovic , Vukovic Bojan , Stepanovic Kristina , Mitrovic Milena , Medic - Stojanoska Milica

Introduction: The incidence of thyroid nodules is increasing. Fine-needle aspiration (FNA) of all thyroid nodules is unnecessary, but it is necessary to provide a more precise identification of those nodules that are potentially malignant in nature. In the literature there are several suggested systems for assessing malignancy of nodules in the thyroid gland.Objective: To determine the differences between EU and ACR TIRADS recommendation for fine-needle ...

ea0049ep116 | Clinical case reports - Pituitary/Adrenal | ECE2017

Primary hyperparathyroidism and primary hyperaldosteronism – cause or coincidence in arterial hypertension – case report

Icin Tijana , Bajkin Ivana , Tomic Dusan , Novakovic-Paro Jovanka , Vukovic Bojan , Prodanovic Jovana , Medic-Stojanoska Milica

Introduction: 30% of the adult population has high blood pressure. About 6% of the hypertension may be caused by primary aldosteronism and very rare by primary hyperparathyroidism. The combination of these two causes is very rare.Case report: Our patient is women (age 50) with a 21 year long history of uncontrolled hypertension. Treatment of hypertension consist of a beta-blocker, calcium channel blockers, angiotensin converting enzyme inhibitor, loop di...

ea0035p94 | Bone and Osteoporosis | ECE2014

Influence of osteoporosis risk factors on extensive suppression of bone metabolism during antiresorptive therapy

Icin Tijana , Novakovic-Paro Jovanka , Vukovic Bojan , Bajkin Ivana , Medic-Stojanoska Milica

Introduction: Some patients develop excessive bone metabolism supression during antiresorptive therapy. Low remodelling rate enables increase in tissue mineralisation density and homogenicity of bone trabeculae. Increase in density makes micro-damage more likely. Increased homogenicity provides less resistance to spread of the micro-cracks and slowed remodelling slows down removal of microdemage. All this leads to increased bone fragility.Aim: To establi...

ea0022p88 | Bone/Calcium | ECE2010

Vitamin D and calcium status in women with postmenopausal osteoporosis

Novakovic-Paro Jovanka , Kovacev-Zavisic Branka , Medic-Stojanoska Milica , Bajkin Ivana , Icin Tijana , Todorovic-Djilas Ljiljana

Many studies show insufficient and inadequate vitamin D and calcium levels in postmenopausal women with osteoporosis, thus emphasising the need for supplementation therapy.Aim of the study: To determine vitamin D (25(OH)D) and ionised calcium levels in women treated for postmenopausal osteoporosis at our Clinic in the course of year 2009.Materials and methods: We prospectively followed up 116 women at the age of 59.38±5.55 (mi...

ea0022p219 | Clinical case reports and clinical practice | ECE2010

Secondary osteoporosis and secondary hyperparathyroidism in patient with Hashimoto thyroiditis and coeliac disease (case report)

Icin Tijana , Kovacev-Zavisic Branka , Novakovic-Paro Jovanka , Bajkin Ivana , Medic-Stojanoska Milica , Todorovic-Djilas Ljiljana

Introduction: Autoimmune thyroid disease is often associated with other autoimmune diseases. Coeliac disease is one of those autoimmune diseases, together with is wide spectrum of intestinal and extraintestinal manifestations. Atrophy of intestinal mucosa, one of the characteristics of coeliac disease, among everything else, leads to poor absorption of l-tyroxine used in therapy of hypothyroidism.Aim and results: We like to present a clinical case of our...

ea0020p145 | Thyroid | ECE2009

Assessment of biochemical parameters during Levothyroxine replacement therapy in hypothyroid patients

Mijovic Romana , Medic-Stojanoska Milica , Curic Nikola , Tonic Stanislava , Kovacev-Zavisic Branka , Djilas-Todorovic Ljiljana

Aim of this study was to evaluate biochemical parameters of thyroid gland function, used in evaluation of levothyroxine (L-T4) dose titration during a long time period in hypothyroid patients.Patients and methods: About 32 hypothyroid women were included in our study. All patients were euthyroid for a long time, treated with levothyroxine replacement therapy, taking an individually titrated daily dosage (50–100 μg). Blood samples...

ea0020p263 | Bone/Calcium | ECE2009

Bone resorption and antiresorptive effect of bisphosphonates related to homocysteinaemia

Icin Tijana , Kovacev-Zavisic Branka , Medic-Stojanoska Milica , Cabarkapa Velibor , Novakovic-Paro Jovanka , Bajkin Ivana

Introduction: Some recent data indicates that high levels of homocysteine (Hcy) can be independent risk factor for osteoporosis and fractures in elderly. There are few explanations how homocysteine influence bone resorption and probably modify effect of therapy for osteoporosis. 1. Hcy interferes with collagen cross-linking. 2. High levels of Hcy specially stimulate resorptive activity of osteoclasts in vitro. 3. Hcy interfere bisphosphonates binding to hydroxyapatite.<...

ea0016p139 | Clinical cases | ECE2008

Biochemical markers of bone in coeliac disease

Radovanov Tijana , Uzurov Vera , Bajkin Ivana , Medic-Stojanoska Milica , Kovacev-Zavisic Branka

Introduction: Prevalence of celiac disease (gluten enteropathy) in general population is around 1:100–300. Half of these patients are women. Most common age for diagnose is third year or third to fourth decade of life, due to mild clinical signs. In the moment of diagnosis, 30% of patients already have lowered bone mineral density (BMD). Pathophysiologic mechanism for lowering BMD is secondary, regulative, intestinal hyperparathyroidism.Aim: To trac...

ea0049ep709 | Obesity | ECE2017

Prevalence of mono-ethyl-hexyl phthalate and mono-ethyl phthalate in Serbian population and their influence on leptin and thyroid function in obesity

Bajkin Ivana , Milic Natasa , Novakovic-Paro Jovanka , Icin Tijana , Prodanovic Jovana , Curic Nikola , Vukovic Bojan , Medic-Stojanoska Milica

Introduction: Phthalates are ubiquitous endocrine disruptors (EDs). EDs induce obesity. MEP and MEHP affect thyroid function.Aim: Estimation of burden of MEP and MEHP in our population, evaluation of leptin in obese MEP and MEHP positive and negative subjects and evaluation of connection between leptin, MEP, MEHP and thyroid indicators in that subgroup. Materials and methods: a cross-sectional study, with 201 subjects divided into MEP/MEHP positive and n...

ea0037ep238 | Calcium and Vitamin D metabolism | ECE2015

Effect of supplementation with vitamin D and calcium to excessive suppression of bone metabolism during antiresorptive therapy

Icin Tijana , Kovacev-Zavisic Branka , Novakovic-Paro Jovanka , Bajkin Ivana , Vukovic Bojan , Percic Ivanka , Kovacev Nemanja , Medic-Stojanoska Milica

Introduction: Long-term therapy with bisphosphonates is considered a risk factor for the development of atypical fractures of the femur. One of the mechanisms of these fractures is excessive suppression of bone metabolism. The supplementation dose of vitamin D and calcium could have an impact on the degree of suppression of bone turnover.The aim: To determine whether the presence or dose of supplementation with vitamin D and calcium during antiresorptive...