Endocrine Abstracts

Objective: Acclimatization to high-altitude is a dynamic process affecting the neuro-endocrine and physiological systems. Psychological well-being is also influenced by hypobaric-hypoxia. Psychic stress is known to influence the hypothalamo–pituitary–adrenal/thyroid axis. However, the involvement/contribution of ‘psychological-performance’ on hormone changes at high-altitude is not known. The objective of this study was to examine: i) the effect of ethnicit...

Background: Arginine vasopressin (AVP) changes during altitude acclimatization is of clinical interest as increases in their plasma levels (with reference to sea-level (SL)) have been associated with fluid retention accompanied by elevated plasma cortisol levels. Studies have reported no change/ decrease in plasma AVP during ‘normal’ acclimatization. This study was conducted to evaluate plasma AVP changes and the associated physiological changes during chronic exposu...

Background and objective: Adaptive process to hypoxia of altitude involves changes in the homeostatic steady state of several endocrine variables which precede and contribute- to many physiologic adaptations. Physiologic responses to altitude-stress exhibit ethnic variation. However, there has been limited characterization of ‘ethnicity effect’ on endocrine responses to high-altitude stress. This is true for enzyme-immunoassay method (EIA) of plasma hormone analysis....