Searchable abstracts of presentations at key conferences in endocrinology

ea0014p277 | (1) | ECE2007

Adrenal incidentalomas: aberrant expression of hormone receptors (preliminary results)

Mena Elena , Sahun Manel , Alià Pedro , Navarro M Ángel , Soler Joan , Villabona Carles

Background: In some patients with adrenal tumors cortisol regulation may be under the control of abnormal or ectopic hormone receptors. The objective of this study is investigate the presence of these aberrant receptors in subjects with adrenal incidentaloma and biochemical criteria of subclinical hypercortisolism.Patients and methods: We studied seventeen patients with adrenal incidentalomas, ten patients with a unilateral tumor (age 48–70, M/F: 4/...

ea0063p269 | Pituitary and Neuroendocrinology 1 | ECE2019

Diabetes insipidus and diabetes mellitus type 2 diagnosed at the same time in a male with langerhans cell histiocytosis

Barcelo Carlos Antich , Soler Guillermo Serra , Font Mercedes Noval , Ribas Elena Mena , Povidano Santiago Tofe , Jimenez Inaki Arguelles , Fernandez Honorato Garcia , Macazaga Vicente Pereg

Introduction: Langerhans cell histiocytosis (LCH) is a rare systemic disease. Diabetes insipidus is the most frequent endocrine alteration and occurs mostly after diagnosis. Others are hypogonadism, growth hormone deficiency (GHD) and alterations in glucose metabolism.Clinical case: A 61-year-old smoker, diagnosed with LCH 9 years ago with pulmonary and hepatic involvement, without treatment, who consulted for asthenia, unquantifiable polyuria, polydipsi...

ea0037ep246 | Calcium and Vitamin D metabolism | ECE2015

Hypocalcaemia due to 22q11.2 deletion syndrome diagnosed in adulthood

Vidal Maria Cabrer , Soler Guillermo Serra , Wos Marzena , Perez Maria Soledad Gogorza , Jimenez Inaki Arguelles , Povedano Santiago Tofe , Ribas Elena Mena , Fernandez Honorato Garcia , Macazaga Vicente Pereg

Introduction: Hypocalcaemia is present in half of the patients with 22q11.2 deletion syndrome (DiGeorge-velocardiofacial syndrome). Most of these cases are diagnosed during childhood.Case report: A 56-year-old man was evaluated for symptomatic hypocalcaemia after undergoing a left nephrectomy because of renal tumour. He had paraesthesia around his mouth and hands and Trousseau’s sign. His past medical history included high blood pressure, type 2 dia...

ea0056p973 | Male Reproduction | ECE2018

Male hypogonadism due to 46, XX Testicular disorder of sex development

Font Mercedes Noval , Soler Guillermo Serra , Portilla Ana Jimenez , Barcelo Carlos Antich , Povedano Santiago Tofe , Ribas Elena Mena , Macazaga Vicente Pereg

Introduction: 46,XX testicular disorder of sex development (DSD) is a rare syndrome, which is characterized by a female karyotype in discordance with a male phenotype. It is presented with primary hypogonadism, gynecomastia and infertility. About 80–90% of 46,XX testicular DSD cases are positive for SRY gene. Appearance of external genitalia and masculinization are usually normal in 46,XX SRY-positive casesClinical case: A 41-year-old male came with...

ea0026p238 | Pituitary | ECE2011

Improvement of acromegalic cardiomyopathy following pituitary apoplexy

Soler Guillermo Serra , Ribas Elena Mena , Llinares Jaume Pons , Ramis Pere Pericas , Medina Sergio Diaz , Perla y Perla Barbara Manga , Jimenez Inaki Arguelles , Povedano Santiago Tofe , Marcet Mercedes Codina , Fernandez Honorato Garcia , Macazaga Vicente Pereg

Introduction: Cardiovascular disease is present in up to 60% of patients diagnosed of acromegaly and is responsible of the major related morbidity and mortality.Case report: A 79-year-old-woman with previous history of diabetes mellitus and hypertension was admitted for acute pulmonary edema. Transthoracic echocardiogram showed a severe left ventricular dysfunction with an ejection fraction of 20%, dilated left ventricle and left atrium with a moderate m...

ea0056p50 | Adrenal cortex (to include Cushing's) | ECE2018

Is the adrenal vein sampling the gold standard diagnostic test for the subtyping of primary aldosteronism?

Portilla Ana Jimenez , Ribas Elena Mena , Bennasar Antonia Barcelo , Ruitort Juan Manuel Martinez , Segurola Cristina Alvarez , Font Mercedes Noval , Barcelo Carlos Antich , Soler Guillermo Serra , Jimenez Inaki Arguelles , Povedano Santiago Tofe , Macazaga Vicente Pereg

Introduction: Primary aldosteronism (PA) is the most common cause of secondary hypertension (5–10%) and it is underdiagnosed. Less than 50% of patients with PA have hypokalemia. The tests for determinate subtype of PA are cross-sectional imaging (adrenal CT or MRI) and adrenal vein sampling (AVS). The AVS seems to be important to direct appropriate therapy and surgery is the preferred treatment for patients with unilateral disease.Material and metho...

ea0081ep663 | Pituitary and Neuroendocrinology | ECE2022

Hypothalamic syndrome secondary to systemic sarcoidosis

Vicente Gil Boix Jose , Soler Guillermo Serra , Font Mercedes Noval , Cubas Javier Bodoque , Raczkowski Meritxell Vin es , Sanmartin Sanchez Alicia , Tofe Povedano Santiago , Ribas Elena Mena , Marcet Mercedes Codina , Alcolea Josefina Olivares , Palou Francisca Caimari , Macazaga Vicente Pereg , ArguElles Imenez Inaki

Introduction: Sarcoidosis is a rare systemic disease where clusters of immune cells form granulomas in various organs of the body. Its prevalence ranges from 1-40 per 100,000 people in Europe. Neurological involvement of the disease occurs in 5-10% of cases, with the hypothalamus-pituitary gland being one of the most commonly affected structures.Clinical Case: A 36-year-old male with a history of hypertension, obesity, asthma and OSAS. He went to the eme...