Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep178 | Calcium and Bone | ECE2022

Sickle cell disease and hyperparathyroidism: case report

Jridi Maysam , Mekni Sabrine , Meriem Adel , Rojbi Imen , Nacef Ibtissem Ben , Mchirgui Nadia , Khiari Karima

Introduction: Primary hyperparathyroidism (pHPT) is a common endocrine disorder usually diagnosed by the presence of elevated serum calcium levels with inappropriate normal or increased parathyroid hormone (PTH) serum levels. This condition has been reported in few cases of patients with sickle cell disease (SCD), a multisystem disorder with acute and chronic complications.Observation: We report a case of a 63-year-old Tunisian woman with a history of ho...

ea0081ep839 | Pituitary and Neuroendocrinology | ECE2022

Diagnosis of Kallmann syndrome in adulthood

Kamoun Elyes , Mekni Sabrine , Adel Meriem , Rojbi Imen , Ben Nacef Ibtissem , Mchirgui Nadia , Khiari Karima

Introduction: Kallmann syndrome is a rare genetic condition characterized by the association of a hypogonadotropic hypogonadism and anosmia. It results from the failure of GnRH cells to migrate to the hypothalamus and lack of development of the olfactory bulb. The main symptom of Kallmann syndrome is delayed or incomplete puberty usually associated with an impaired sense of smell. We herein describe a case of Kallmann syndrome discovered at the age of 57 years old.<p class...

ea0081ep1110 | Thyroid | ECE2022

A case of graves’ orbitopathy in a patient sero-negative for TSH receptor autoantibody

Besrour Chayma , Imen Rojbi , Sabrine Mekni , Adel Meriem , Nadia Mchirgui , Ibtissem Ben Nacef , Karima Khiari

Introduction: The orbit represents the second target after the thyroid gland in autoimmune dysthyroidism. In 80% of cases, endocrine orbitopathy occurs as a result of hyperthyroidism, especially Grave’s disease (GD). Males are rarely affected but the damage is more serious.Observation: We report the case of a 52-year-old patient, an active smoker (35 Pack-Year), transferred from the neurology department for treatment of bilateral malignant exophthal...

ea0063p425 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Insulinoma: a case series of a tertiary care center

Jemel Manel , Jemel Manel , Kandara Hajer , Adel Meriem , El Guich Dorra , Jemni Houda , Kammoun Ines

Introduction: Insulinoma is rare tumor with an incidence of 1 in 250,000 patient-years. It presents with repeated episodes of hypoglycemia due to endogenous hyperinsulinemia, which occurs mostly in the fasting state. Insulinomas are usually sporadic, solitary, benign and encapsulated small lesions and majority of them measure <2 cm in diameter. They pose a challenge for pre-operative localization.Materials and methods: A retrospective study of patien...

ea0063ep120 | Pituitary and Neuroendocrinology | ECE2019

Management challenge of child hood Cushing disease

Adel Meriem , Jemel Manel , Kandara Hajer , Kalthoum Mahdi , Nagi Sonia , Kammoun Ines

Introduction: Cushing’s syndrome (CS) is rare in children. The most common cause of CS in children is exogenous or iatrogenic CS. The most common cause of endogenous CS is Cushing disease (CD). Pediatric CD is almost always caused by a pituitary microadenoma. Here we present a rare case of (CD) related to pituitary macroadenoma.Clinical observation: An 11 year old boy presented with complaints of excessive appetite and progressive weight gain. He ha...

ea0070aep407 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Microangiopathy and cardiovascular risk in type 2 diabetic population

Kalthoum Mehdi , Ben Nacef Ibtissem , Rojbi Imen , Adel Meriem , Mechirgui Nadia , Khiari Karima

Introduction: Type 2 diabetes is a springboard to metabolic and cardiovascular complications. The objective of our work was to investigate the different cardiovascular risk factors in diabetic type 2 population, and study relation between the level of cardiovascular risk and the occurrence of degenerative complications.Patients and Methods: Retrospective study including 149 patients with type 2 diabetes consultant at the Department of Endocrinology at th...

ea0070aep704 | Pituitary and Neuroendocrinology | ECE2020

A rare etiology of hyperprolactinemia: Factitious hypoglycemia

Kalthoum Mehdi , Gharbi Radhouan , Kandara Hajer , Adel Meriem , Jemel Manel , Kammoun Ines

Introduction: While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Factitious hypoglycemia a rare case of induced hyperprolactinemiaCase report: We report a case of 17-years-old girl presented to with sever hypoglycemia mesured at 30 mg/dl. The patient had no significa...

ea0070ep282 | Pituitary and Neuroendocrinology | ECE2020

Pituitary metastasis as a rare cause of diabetes insipidus

Kalthoum Mehdi , Kandara Hajer , Adel Meriem , Jmel Manel , Gharbi Radhouen , Kammoun Ines

Introduction: The most common cause of diabetes insipidus is idiopathic. In some rare cases, it can be secondary to metastasis to hypothalamic–pituitary region.Case report: We report a case of 68-years-old female patient presented to our clinic with complaints of polyuria and polydipsia. She had medical history of breast adenocarcinoma 6 years ago treated with surgery, neoadjuvant radiotherapy and 8 cycles of chimiotherapy. On physical examination ...

ea0073aep41 | Adrenal and Cardiovascular Endocrinology | ECE2021

A case of adrenergic myocarditis in pheochromocytoma mimicking COVID-19 pneumonia

Adel Meriem , Rojbi Imen , Majdoub Marwa , Mchirgui Nadia , Lakhoua Youssef , Nacef Ibtissem Ben , Khiari Karima

IntroductionPheochromocytomas are rare catecholamine-producing neuroendocrine tumors derived from the sympathetic or parasympathetic nervous system. The clinical presentation of pheocromocytoma has varying forms, which makes diagnosing it challenging. Here, we report a case of Adrenergic cardiomyopathy mimicking COVID-19.Case reportA 40-year-old woman with a history of pulmonary edema during cesarean delivery...

ea0073aep393 | Endocrine-Related Cancer | ECE2021

Severe hypoglycemia: First manifestation of an advanced hepatocellular carcinoma

Elhaj Wiem Ben , Rojbi Imen , Adel Meriem , Mchirgui Nadia , Lakhoua Youssef , Nacef Ibtissem Ben , Khiari Karima

BackgroundHypoglycemia is a well-established as a serious paraneoplastic complication of hepatocellular carcinoma (HCC). However, hypoglycemia presenting the first presentation of HCC is not frequent. In this regard, we present the case of a patient who had hypoglycemia as first manifestation of HCC.ObservationA 55yearold man presented to the Emergency Department with loss of consciousness preceded by dizzine...