ea0050p187 | Clinical Biochemistry | SFEBES2017
Adaway Jo
, Miller Ann Marie
, Monaghan Phillip
, Merrett Nicola
, Keevil Brian
, Owen Laura
Sex hormone binding globulin (SHBG) is a glycoprotein which binds hormones such as testosterone. Around 97% of circulating testosterone is bound to SHBG and is therefore biologically unavailable; approximately 23% of testosterone is free or loosely bound to proteins such as albumin, and is biologically active, or bioavailable. Free testosterone is very technically challenging to quantify; in order to circumvent this problem, equations are used...