ea0004s11 | Ageing and cellular senescence | SFE2002
Merry B
It is considered that reactive oxygen species (ROS) and free radicals in general, are involved in a variety of physiological and pathological processes including degenerative disease and probably ageing. Age-related accrual of oxidative stress is a balance between ROS-induced generation rates and the activity of antioxidant defence enzymes, tissue antioxidant concentrations, repair processes, chaperone protein activity and molecular and cellular turnover rates. End-point measu...