ea0063p1039 | Interdisciplinary Endocrinology 2 | ECE2019
Pelsma Iris
, Claessen Kim
, Ramos Yolande
, Meulenbelt Ingrid
, Biermasz Nienke
Introduction: Increased insulin-like growth factor 1 (IGF-1) levels in patients with acromegaly are associated with clinical and radiological osteoarthritis (OA). We aimed to elucidate whether serum IGF-1 levels differ in patients with primary OA as compared to healthy controls and whether genetic variants known to affect serum IGF-1 levels are also associated with primary OA.Methods: Patients from the GARP study with familial generalized OA (n=...