Endocrine Abstracts

Introduction: Non-classical congenital adrenal hyperplasia (NCCAH) is considered to be a common monogenic inherited disease, with an incidence range from 1:500 to 1:100 births worldwide. NCCAH is often peri or post pubertal pauci or even asymptomatic. We report the case of a young girl with severe hirsutism and sexual ambiguity, despite late disclosure.Observation: This is the case of a 16-year-old girl, with a history of menarche at the age of 14, prese...

Introduction: TSH-secreting pituitary neuroendocrine tumor (TSH-PitNET) is the rarest pituitary tumors. Most TSH-PitNETs are secreting, with a biological profile of inappropriate TSH secretion (moderately elevated TSH, elevated FT3 and FT4).Observation: We report the case of a 69-year-old patient, with a history of total thyroidectomy in 2014 for multinodular goiter, hospitalized for suspected levothyroxine pseudo-malabsorption. Despite doses above 2 &#1...

Te paraneoplastic Cushing’s syndrome represents 9 to 18% of ACTH-dependent endogenous hypercorticisms; which poses, in clinical practice, two types of problems:– on the one hand, the differential diagnosis with Cushing’s disease, when well differentiated and morphologically undetectable endocrine tumors are involved.– on the other hand, the control of hypercortism, most often major in metastatic neuroendocri...

Introduction: Mitotane is an adrenolytic drug that is used as an adjuvant to treat adrenocortical carcinoma, The side effects of lysodren are numerous, but some of them are less known. We report a case of ovarian cyst in a woman of childbearing age. It is a 26 years old patient treated with Lysodren® for a locoregional recurrence of an adrenal cacinoma stage II of the ENSAT. After 9 months of treatment, the patient presented an amenorrhea, with the appearance of a large o...

Introduction: Oncocytomas of adrenal glands are extremely rare and usually present as incidentally detected masses. The aim of this presentation is to report tow cases of a virilizing androgen-secreting adrenal oncocytoma.Case description: Case 1: A 27-year-old female was admitted to our clinic with a 116 mm left adrenal incidentaloma. The patient’s main symptom was hirsutism. Upon investigation, elevated values of testosterone, and DHEA-S were foun...

Introduction: Vitamin D deficiency seems to be common in pregnant women and would be associated with an increased risk of maternal and fetal poor outcomes.Aim of the study: Determine the prevalence and the main risk factors for vitamin D deficiency in pregnant women living in a locality of Algiers.Material and method: It is a cross-sectional prospective and descriptive study. 310 pregnant women of west Algiers were followed during ...

Oncocytary cells adrenal adenoma or adrenal oncocytoma is an extremely rare tumor, mainly composed by oncocytomes. The diagnosis is exclusively confirmed on histological findings. There are about 50 cases published in the scientific reviews, of which only one case described a pregnant woman.We report an observation about a 31 years old patient, with no personal antecedent, explored in our unit for an adrenal masse, measuring 71×58×46 mm discove...

Post parthyroïdectomy hypocalcemia is a frequent situation, generally due to a definitive or transient hypoparathyroïdism.The ‘Hungry bone syndrome’, is a rare severe hypocalcemia etiology, assigned to an excessive osseous avidity, occurring in intense bone remodeling situations like fibrous osteitis or renal osteodystrophy.We report a case of a 41 years old woman, presenting a chronic renal failure, at hemodial...

Introduction: Pituitary apoplexy is caused by an infarction or a haemorrhage in a pituitary adenoma manifesting in acute headaches, consciousness impairment, endocrine features, and moderate to severe visual loss, with chiasmal syndrome or oculomotor palsies.Case report: We describe here a case of a 25 years old woman, followed in our institute for a Cushing disease, and who underwent a pituitary apoplexy 24 h after a standard low-dose dexamethasone supp...

Erdheim Chester disease (ECD) is a non langheransian rare histiocytosis, with around 500 cases described worldwide since its discovery for the first time in 1930 by Jakob Erdheim et William Chester. It is a multivisceral disease, characterized by a proliferation of abnormal histocytes CD68 positive and CD1a negative, including a retroperitoneal and perirenal fibrosis, a peri-aortitis, an osteosclerosis of the lower limbs and sometime an exophthalmia or an diabetes insipidus. H...