Searchable abstracts of presentations at key conferences in endocrinology

ea0022p289 | Diabetes | ECE2010

Association of diabetes mellitus with thalassaemia and sickle cell disease

Thisiadou Katerina , Karamouzis Ioannis , Arampatzi Stella , Tomos Kostantinos , Michailidou Despoina

Background: The majority of complications in transfusion dependent thallasemic and with sickle cell anemia patients are due to iron overload. This is responsible for the beginning of haemosiderosis, clinical symptoms and dysfunction of important systems, specially after the 2nd decade of life. The increase of the iron accumulation is caused by hemolysis, high iron absorbance and mainly by transfusion treatment. The appearance of diabetes mellitus depends on the significance an...

ea0022p80 | Bone/Calcium | ECE2010

Secondary hypoparathyroidism in thalassaemia and sickle cell anaemia

Thisiadou Katerina , Karamouzis Ioannis , Arampatzi Stella , Chalvatzi Kiriaki , Hasapopoulou Eleni , Michailidou Despoina

Background: The diagnosis of hypoparathyroidism, a clinical situation characterised by reduced production of parathyroid hormone despite the low calcium level, depends on patientÂ’s anamnesis, clinical aspect and the biochemical parameters.Thalassaemia, an inherited autosomal recessive blood disease, caused by the reduced capacity of erythroblasts to synthesize one of the chains that build up hemoglobine. The combination of transfusion and chelation ...

ea0022p81 | Bone/Calcium | ECE2010

Abnormalities in calcium, phosphorus and parathyroid hormone in patients with end stage chronic kidney disease on hemodialysis

Thisiadou Katerina , Karamouzis Ioannis , Arampatzi Stella , Tsolakidou Alexandra , Sioulis Athanasios , Michailidou Despoina

Introduction: The decline of renal function is closely associated to increased parathyroid hormone secretion, resulting to secondary hyperparathyroidism because of: 1) hypocalcemia; 2) hyperphosphatemia; 3) reduced activity of calcitriol; 4) skeletal resistance to the calcemic action of parathyroid hormone (PTH) and 5) reduced secretion of the calcium-sensing receptor (CaSR) in the parathyroid glands.The retention of phosphorus is considered to take an i...