Searchable abstracts of presentations at key conferences in endocrinology

ea0026p495 | Bone/calcium/Vitamin D | ECE2011

Overweight and risk for osteoporosis

Polovina Snezana , Nemet Klara Tucic , Micic Jelena , Vulovic Koviljka Milenkovic , Micic Dusan , Micic Dragan

BMI over 30 kg/m2 is associated with lowest risk for osteoporosis and hip fracture in both sex. Increased body fat mass is followed with greater hip fracture risk, independently of BMI.Aim: Evaluate risk for osteoporosis in postmenopausal female with BMI 25–29.9 kg/m2 and influence of body fat mass on mineral bone density in overweight women.Material and methods: One hundred postmenopausal female, age 48&...

ea0026p607 | Clinical case reports | ECE2011

Hypoglycemia in patient with large intraabdominal tumor

Ivovic Miomira , Vujovic Svetlana , Tancic-Gajic Milina , Marina Ljiljana , Djukic Vladimir , Micic Dusan , Micic Dragan

Introduction: Various non pancreatic tumors can cause hypoglycemia. Usually they are mesenchymal, retroperitoneal tumors or fibrosarcomas. Hemangiopericytoma is a rare type of mesenchymal tumor, which mostly develops in soft tissue and originates from the Zimmermann’s pericyte (modified smooth muscle cells).Case report: Fifty-nine-years old female patient with hypoglicemia was addmited to our department. Physical finding showed mild obesity and hype...

ea0022p332 | Diabetes | ECE2010

The mean HbA1c values in T2DM according a therapy regiments

Polovina Snezana , Nemet Klara Tucic , Micic Dusan , Micic Jelena , Micic Dragan

Aim: To calculate mean HbA1c values in patients with type 2 diabetes mellitus in different therapy regiments.Material and methods: Ninety-nine diabetic persons was divided in three groups: group I (n=33) on oral hypoglucemic agents, group II (n=33) on one or two doses of insulin and group III (n=33) on intensive insulin therapy. We have calculated the mean values of HbA1c on the begining and 6 months after start of therapy regiment.<...

ea0035p765 | Obesity | ECE2014

GLP-1, insulin and glucose levels during mixed test meal before and after gastric bypass surgery in obese patients

Micic Dragan , Polovina Snezana , Jeremic Danka , Micic Dusan , Sumarac-Dumanovic Mirjana

Introduction: Gastric bypass surgery in obese patients results in weight loss, changes in gastrointestinal and pancreatic hormones and improvement of insulin sensitivity.Methods: GLP-1, insulin and glucose levels were measured after test meal (Fresubin drink a 200 ml; 200 kcal, 15% protein, 30% fat and 55% carbohydrate) before (day 0) and 5, 90 and 180 days after gastric bypass surgery. Glycaemia (mmol/l; glucose oxidase);GLP-1 (Active 7–36) (pM/l; ...

ea0022p331 | Diabetes | ECE2010

Transient insulin resistance during the laparoscopic versus open cholecystectomy

Micic Dusan , Polovina Snezana , Micic Jelena , Loncar Zlatibor , Micic Dragan , Djukic Vladimir

Aim: The aim of our study was to investigate is surgical stress induce alterations in insulin sensitivity in the course of cholecystectomy performed in two differnt procedures: as a open surgery and as laparascopic operation.Material and methods: The homeostasis assessment model (HOMA) was used to determine insulin sensitivity before and in the first, third and seventh day after the operation. Patients were divided int two groups: group A (open cholecyst...

ea0032p784 | Obesity | ECE2013

PTH one year after gastric bypass in morbidly obese patients

Polovina Snezana , Micic Dragan , Gligorijevic Jelena , Sumarac-Dumanovic Mirjana , Cvijovic Goran , Stamenkovic-Pejkovic Danica , Milin Jelena , Micic Dusan , Jeremic Danka

Introduction: After gastric bypass, gastric secretion decreased and resorption of minerals and vitamins may be compromised. Lower resorpion of serum calcium and vitamin D could stimulate PTH secretion after restictive and malabsorptive bariatric procedures.Methods: We have measured serum calcium, D vitamin and PTH in patients (n=50, 17 males and 33 females) 6 and 12 months after R en Y gastric bypass, 38.6±12.6 years of age, with BMI 43&#17...

ea0026p170 | Neuroendocrinology | ECE2011

Metabolic encephalopathy and quadriparesis induced by severe hyponatremia in the patient with Sy Seehan

Bogdanovic Jelena , Perusko Radmila Stojanovic , Popovic Dragana , Dzomlija Radojka , popovic Vera , Ercegovac Marko , Bogdanovic Ljiljana , Micic Dusan

Sy Sheehan or postpartal pituitary necrosis presents with symptoms and signs of hypopituitarisms. It is usually a consequence of complicate delivery followed by intensive uterine bleeding. Diagnosis can be delayed years after delivery, up to 20 years.We present a case of 51-year-old female patient. She was admitted in the department of neurology in the Emergency center, Belgrade, with disturbance of consciousness. Few days before she felt leg weakness an...

ea0037gp.12.07 | Diabetes and obesity – Translational diabetes | ECE2015

GLP-1 (Active 7-36) secretory response after test meal in obese patients before and 5; 90 and 180 days after bariatric gastric bypass surgery

Micic Dragan , Polovina Snezana , Sumarac-Dumanovic Mirjana , Gregoric Pavle , Cvijovic Goran , Ignjatovic Svetlana , Dajak Marjana , Micic Dusan , Stamenkovic-Pejkovic Danica , Jeremic Danka

There are different explanations concerning observed improvement of glucose control after baiatric gatric bypass surgery. The aim of our study was to investigate GLP-1 response after test meal (Fresubin drink a 200 ml; 200 kcal, 15% protein, 30% fat and 55% carbohydrate) before (day 0) and 5; 90 and 180 days after gastric bypass surgery. Glycaemia (mmol/l; glucose oxidase) and GLP-1 (Active 7-36) (pM/l; ELISA, ALPCO diagnostics) were determined in 41 obese patients (age: 37.86...

ea0037ep385 | Diabetes (pathiophysiology &amp; epitemiology) | ECE2015

Surgical trauma and insulin resistance

Polovina Snezana , Micic Dusan , Loncar Zlatibor , Sumarac-Dumanovic Mirjana , Savic Predrag , Cvijovic Goran , Resanovic Vladimir , Zoric Svetlana , Stamenkovic-Pejkovic Danica , Djukic Vladimir , Micic Dragan

Introduction: Different surgical procedures are followed by alteration in insulin sensitivity. The aim of our investigation was to analysed the influence of major (open cholecystectomy) and minor surgical stress (laparoscopic cholecystectomy) on insulin resistance.Methods: Insulin resistance was calculated by HOMA-IR before surgery and at 1st, 3rd, and 7th day after the elective operations. All participants were divided in two groups: group A with open c...

ea0037ep564 | Obesity and cardiovascular endocrinology | ECE2015

Haematopoietic system 3 years after gastric bypass

Polovina Snezana , Gligorijevic Jelena , Sumarac/Dumanovic Mirjana , Gregoric Pavle , Kendereski Aleksandra , Cvijovic Goran , Zoric Svetlana , Stamenkovic/Pejkovic Danica , Micic Dusan , Jeremic Danka , Gligic Ana , Divnic Aleksandra , Micic Dragan

Bariatric surgery, especially malapsorptive procedures like gastric bypass, can lead to anaemia due to lack of iron absorption as well as vitamins essential for the normal functioning of the hematopoietic system.Methods: We have analysed changes in red blood cells (RBC), haemoglobin (Hb), white blood cells (WBC), serum iron (Fe), and vitamin B12 3 years after gastric bypass in 142 morbidly obese patients (female, n=108 and male, n=34). ...