Searchable abstracts of presentations at key conferences in endocrinology

ea0022p649 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Aftercare in patients with Cushing's disease and acromegaly: is there room for improvement?

Honegger Juergen , Milian Monika , Psaras Tsambika

Objective: Evaluation of aftercare, medical therapy and remission rate in Cushing’s disease (CD) and acromegaly (AC).Methods: Of 58 CD and 83 AC patients operated over 10 years were carefully evaluated. The patients received a disease-related questionnaire and were invited for a follow-up at the outpatient clinic of the Department of Neurosurgery. 33 CD and 52 AC patients returned the questionnaire, 25 CD and 37 AC patients participated personally. ...

ea0022p650 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Persistent hypocortisolism in Cushing's disease and persistent comorbidities in acromegaly determine neurocognitive function and quality of life after surgical treatment

Psaras Tsambika , Honegger Juergen , Milian Monika

Objective: Cushing’s disease (CD) and acromegaly (AC) are associated with psychological and psychiatric problems. Both pathologies cause a severe impairment in quality of life (QoL) that can persist even if biochemical remission and cure are achieved. The aim of the study was to investigate the influence of the current disease status (remission vs. no remission) on neurocognitive function and QoL in treated CD and AC patients. The second objective was to determine predict...

ea0022p651 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Demographic factors and the presence of comorbidities do not promote early detection of Cushing's disease and acromegaly

Psaras Tsambika , Milian Monika , Honegger Juergen

Objective: The aim of the study was to analyze the time-to-diagnosis interval in patients with Cushing’s disease (CD) and acromegaly (AC), to assess factors that promote early disease detection and to investigate the medical fields diagnosing the pathologies.Design: Case-record retrospective study.Patients: CD and 52 AC patients operated between June 1998 and December 2007.Measurements: All patients rece...

ea0035p7 | Adrenal cortex | ECE2014

Favorable long-term outcome of bilateral adrenalectomy in Cushing's disease

Osswald Andrea , Plomer Eva , Dimopoulou Christina , Milian Monika , Blaser Rainer , Ritzel Katrin , Mickisch Anne , Knerr Ferengis , Stanojevic Milan , Hallfeldt Klaus , Schopohl Jochen , Kuhn Klaus A , Stalla Gunter , Beuschlein Felix , Reincke Martin

Objective: Bilateral adrenalectomy (BADX) is an important treatment option for patients with Cushing’s syndrome (CS). The outcome of this procedure has not been studied well.The aim was to analyze long-term outcome of CS patients treated with BADX.Design: Fifty patients with BADX treated since 1990 in two German centers were identified. 34 patients had Cushing’s disease (CD), nine ectopic Cushing-syndrome (ECS), and seven...