Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep786 | Obesity | ECE2016

Chemerin correlates with obesity and metabolic syndrome and decreases after weight loss in children

Tan Xinrui , Li Min , Xiao Yanfeng

Introduction: Chemerin is a pro-inflammatory adipokine, which has been shown as a mediator between obesity and metabolic syndrome (MetS). The aim of this study was to evaluate the associations of chemerin with insulin resistance and the effects of lifestyle interventions on circulating chemerin levels in Chinese obese children.Methods: A cross-sectional study was conducted among 225 obese children (101 with MetS and 124 without MetS) and 119 lean control...

ea0037ep1270 | Clinical Cases–Thyroid/Other | ECE2015

Severe hypocalcaemia and hypomagnesaemia secondary to omeprazole

Min-Li Teo Claire , Quek Timothy Peng Lim , Abdul Shakoor Shaikh A K K

Introduction: Proton pump inhibitors (PPIs) are commonly prescribed drugs. We report a case of severe hypocalcaemia secondary to omeprazole-induced hypomagnesaemia.Case report: A 85-year-old Chinese man with stage 4 chronic kidney disease was admitted to our hospital in Jun 2014 with vomiting and weakness. On admission, he was severely hypocalcaemic (adjusted calcium 1.37 mmol/l (RI: 2.15–2.58)) and hypomagnesaemic (Mg 0.1 mmol/l (RI: 0.7–1.0))...

ea0037oc2.1 | Reproduction | ECE2015

Decanoic acid inhibits androgen production in vitro and in vivo by regulating HSD3B2: a promising drug candidate for the management of hyperandrogenism in polycystic ovary syndrome

Lee Bao Hui , Tan Huey Min , Li Yu , Zhang Zhiwei , Indran Inthrani Raja , Li Jun , Yong Eu Leong

Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder characterized by hyperandrogenism in women, with a high incidence of insulin resistance. Decanoic acid (DA), a naturally occurring 10-carbon fatty acid, has been shown to improve insulin sensitivity and lipid profile in an in vivo model of diabetes without the induction of weight gain. However, the effects of DA on androgen production has not been explored.Aim: The objective o...

ea0037ep786 | Pituitary: clinical | ECE2015

Cushing's Syndrome: An ominous and commonly forgotten cause of hypokalaemia

Seow Cherng Jye , Ng Zhiguang , Teo Claire Min-Li , Lum Grace , Chow Minyang , Ong Chin Ee , Lai Tian Ray , Ryanputra Davin

Introduction: We report a patient with hypokalaemia secondary to Cushing’s syndrome (CS) to reinforce this commonly forgotten association.Case report: A 57 years old lady with newly diagnosed hypertension, hyperlipidaemia and diabetes mellitus presented with persistent hypokalaemia for evaluation. She had tinea corporis but otherwise did not look Cushingoid. Investigations: K 2.6 (RI: 3.50–5 mmol/l), HCO3 35 (RI: 19–31 mmol/l), ...

ea0037ep854 | Thyroid cancer | ECE2015

Primary thyroid lymphoma: an ominous and commonly forgotten association with Hashimoto's thyroiditis

Seow Cherng Jye , Ryanputra Davin , Lai Tian Ray , Ong Chin Ee , Chow Minyang , Lum Grace , Teo Claire Min-Li , Ng Zhiguang

Introduction: Primary thyroid lymphoma (PTL) is rare and constitutes 2–5% of thyroid malignancies. The risk however increases with background Hashimoto’s thyroiditis. (HT) We report a patient with HT complicated by thyroid lymphoma and did a literature review on this topic.Case presentation: A 61-years-old Chinese lady with background HT on levothyroxine presented with an enlarging goitre of 6 months duration. There was weight loss of 3–4 ...