Searchable abstracts of presentations at key conferences in endocrinology

ea0086p79 | Metabolism, Obesity and Diabetes | SFEBES2022

Severe rhabdomyolysis secondary to rapid correction of hyponatremia in a patient with psychogenic polydipsia

Minhas Raisa , Shekhda Kalyan , Palan Jessal , Vogazianou Artemis

Patients with chronic schizophrenia and psychosis are prone to develop hyponatremia secondary to psychogenic polydipsia. Hyponatremia secondary to water intoxication and its rapid correction are linked with rhabdomyolysis, an under-recognized yet serious condition. We report a case of 31 year old male with schizophrenia on Risperidone, who was brought to the emergency due to an unwitnessed fall and confusion. Serum sodium was 111 mmol/l, urine osmolality 55 mosm/kg and urine s...

ea0086p289 | Thyroid | SFEBES2022

Graves’ disease with benign ethnic neutropenia-a grave combination

Minhas Raisa , Shekhda Kalyan , Palan Jessal , Vogazianou Artemis , Richards Huw , McMillan Annabel

Benign Ethnic Neutropenia (BEN) is a common form of neutropenia defined as an absolute blood neutrophil count (ANC) of < 1.5 x 109/l, usually observed in Afro-Caribbeans. These patients are not at increased risk of infection despite their neutropenia, unless they are on medications which can cause neutropenia. Amongst these drugs antithyroid medications are known to cause agranulocytosis defined as ANC of <500/μl. We report a case of 24 years old male w...

ea0090ep832 | Pituitary and Neuroendocrinology | ECE2023

An Atypical Presentation of Hypopituitrism

Minhas Raisa , Bashir Keefah , Mitchell Catherine , Ling Yong , Tarigopula Giridhar , Alansari Mustafa , Wernig Florian , Tomlinson James

A 48-year-old male presented with headache, cough and recurrent nose bleeds. Clinical examination showed saddle shape nose deformity. His past medical history included primary hypothyroidism diagnosed at the age of 10 years, was taking levothyroxine. His brother had a Rathke’s cleft cyst, surgically removed. His blood test were as follows: Sodium 125mmol/l, TSH 0.10mU/l, free T4 10.2pmol/l, freeT3 2.6pmol/l, cortisol < 28nmol/l, prolactin 240mU/l, FSH 1.8U/l, LH 0.3U/...

ea0091wg4 | Workshop G: Disorders of appetite and weight | SFEEU2023

Extreme hyperandrogenism secondary to PCOS with weight gain

Bashir Kefah , Tarigopula Giridhar , Mitchell Catherine , Al-Ansari Mustafa , Ling Yong , Minhas Raisa

A 45-year-old female presented with secondary amenorrhea. Since menarche, her period has been irregular, which she initially managed with oral pills, which were discontinued in 2009. Subsequently, she does have complete secondary amenorrhoea. She has hirsutism at the age of 20. Which was initially well controlled with oral contraceptive pills but has been getting worse over the years. Ferriman-Gallwey’s score was high. She also stated that her weight had been steadily inc...

ea0086p194 | Endocrine Cancer and Late Effects | SFEBES2022

The incidence and clinical significance of metabolically active brown adipose tissue in patients with pheochromocytomas and paragangliomas: A retrospective cohort study, systematic review and meta-analysis

Onyema Michael , Ostarijas Eduard , Minhas Raisa , Roy Aparajita , Kearney Jessica , Omran Asma , Zair Zoulikha , Reynolds Saira , Mulholland Nicola , Corcoran Benjamin , Halim Mohammad , Aylwin Simon , Dimitriadis Georgios K

There is limited research into the impact of active brown adipose tissue (aBAT) in patients with phaeochromocytomas and paragangliomas (PPGLs). A small body of evidence has shown that patients with PPGL patients can exhibit a high prevalence for aBAT recognized as ranging between 8 - 28% without specific correlation to germline mutations. Furthermore, it has been suggested that aBAT may be linked to increased mortality. Systematic searches of the Medical Literature Analysis an...