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ea0073yi2 | Young Investigator Awards | ECE2021

Efficacy of the Anti-BAFF monoclonal antibody belimumab vs methylprednisolone in active moderate-severe graves’ orbitopathy: Preliminary analysis of a randomized controlled trial

Vittoria Favero , Currò Nicola , Campi Irene , Lazzaroni Elisa , Covelli Danila , Vannucchi Guia , Dazzi Davide , Muller Ilaria , Minorini Valeria , Guastella Claudio , Maura Arosio , Salvi Mario

BackgroundSerum B cell stimulating factor (BAFF) has been shown to be elevated in Graves disease (Vannucchi 2012). In addition, BAFF and its receptor have been shown to be expressed on lymphocytes infiltrating the thyroid in Graves disease and also on thyrocytes (Campi 2015).AimsWe tested in a single-blind randomized controlled trial (EudraCT 2015–002127–26) whether the administration ...

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Endocrine Abstracts

Efficacy of the Anti-BAFF monoclonal antibody belimumab vs methylprednisolone in active moderate-severe graves’ orbitopathy: Preliminary analysis of a randomized controlled trial

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