Endocrine Abstracts

Introduction: Metastatic well-differentiated rectal neuroendocrine neoplasms (NENs) are heterogeneous and considered ’immune-cold.’ Standard treatments include somatostatin analogues, peptide receptor radionuclide therapy and chemotherapy. We report a case where a patient responded to third-line immunotherapy, despite the absence of predictive biomarkers.Case Presentation: A 60-year-old man was referred for colonoscopy following bowel cancer sc...