Searchable abstracts of presentations at key conferences in endocrinology

ea0029s46.1 | Chronic inflammation and insulin resistance | ICEECE2012

AIMing at metabolic syndrome: towards development of novel therapies for modern metabolic diseases via macrophage-derived AIM

Miyazaki T.

Metabolic syndrome is a cascade of metabolic diseases starting with obesity and progressing to atherosclerosis and is often fatal because of serious cardiovascular problems such as heart/brain infarction and hemorrhage. Accumulating evidence has revealed a critical involvement of inflammatory responses triggered by lesional macrophages in its pathogenesis. Importantly, we found that macrophages are associated with the progression of these diseases not only in the induction of ...