Searchable abstracts of presentations at key conferences in endocrinology

ea0077p85 | Neuroendocrinology and Pituitary | SFEBES2021

Clinical presentation of 209 surgically operated non-functioning pituitary macroadenomas

Edwards Mared , Hayhurst Caroline , Mohamed Amr , Davies J Steve , Rees D Aled , Lansdown Andrew

Background: The clinical presentation of non-functioning pituitary adenomas (NFAs) can range from an incidental finding on imaging to pituitary hormone deficiencies and visual compromise.Objective: To assess the clinical presentation of patients who had undergone surgical resection of histologically proven NFAs.Methods: Patients presenting to the University Hospital of Wales, Cardiff, with non-functioning pituitary adenomas (histol...

ea0098c56 | Clinical – Surgery/Applied Pathology | NANETS2023

Comparative gene expression and pathway analysis of neuroendocrine neoplasms in relation to clinical outcomes and tumor location

Laderian Bahar , Saberzadeh Ardestani Bahar , Chen Yanwen , Mohamed Amr , Ni Ying , Mundi Prabhjot

Background: Neuroendocrine malignancies are heterogeneous cancers with varied clinical outcomes. The molecular landscape driving this heterogeneity has not yet been fully characterized. We aimed to investigate the gene expression profiles of neuroendocrine neoplasms, in relationship to baseline clinicopathological features and clinical outcomes, to elucidate underlying biology and potential therapeutic targets.Methods: Patients with neuroendocrine tumors...

ea0070aep700 | Pituitary and Neuroendocrinology | ECE2020

Disconnection hyperprolactinaemia and its correlation with tumour size: A study of 210 patients with histologically proven non-functioning pituitary macroadenomas

Das Arpan , Elalfy Omar , Hayhurst Caroline , Goetz Pablo , Mohamed Amr , Steve Davies J , Aled Rees D , Lansdown Andrew

Background: Serum prolactin levels at presentation can be useful in distinguishing between non-functioning pituitary macroadenomas and prolactinomas in order to guide appropriate therapy. Although thresholds have been suggested to distinguish between the two tumour-types, there remains some debate regarding discriminatory levels.Objective: To assess the baseline serum prolactin levels in a series of patients with histologically-proven non-functioning pit...